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spy187
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Dimenhydrinate
Trade name:
Gravol, Dramamine
-
Dimenhydrinate
Class:
- antiemetic,
- antihistamine
- anticholinergic
- antivertigo
-
Dimenhydrinate
Action:
Antiemetic/antivertigo: inhibits nausea and vomiting by centrally depressing sensitivity to the labyrinth apparatus that relays stimuli to the chemoreceptor trigger zone and stimulates the vomiting center of the brain
-
Dimenhydrinate
Indications:
Nausea, vomiting
-
Dimenhydrinate
Contraindications:
- Hypersensitivity (contains benzyl alcohol)
- Seizures
- Any condition which may be worsened by anti-cholinergic effects
-
Dimenhydrinate
Adverse effects:
- Can cause sedation
- dry mouth
- blurred vision
- urinary retention
-
Dimenhydrinate
Onset:
Immediate
-
Dimenhydrinate
Duration:
4-7 hours Peak :1-4 hours
-
Dimenhydrinate
Adult Dosage:
- 25 – 50 mg slow IVP
- 50 – 10 mg IM
- Note: IV dose must be diluted with NS to 10 ml
-
Dimenhydrinate
Pediatric Doseage:
- 1 mg/kg IM or slow IVP (diluted)
- 2 – 5 years do not exceed 25 mg
- 6 – 12 years do not exceed 50 mg
-
Dimenhydrinate
Route:
Route: IV, IM
-
Dimenhydrinate
Interactions/Precautions:
- Seizure disorders
- Asthma
- Patients with increased intraocular pressure or angle-closure glaucoma.
- Undiluted solution is irritating to the veins and may produce sclerosis
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