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Cholesterol is a precursor for what three components?
What are the three methods of cholesterol influx?
de novo synthesis
What are the 3 methods for cholesterol excretion?
free cholesterol in bile
What are the two methods in activating the RLE, HMG CoA Reductase?
What are the two jobs on intestinal flora on bile salts?
Deconjugate = back to bile acids (cholic, chenodeoxycholic)
Dehydroxylate = secondary bile acids (deoxycholic, litholic)
What are the two conjugates added to bile acids to form bile salts?
Glycine = glycocholic acid
Taurine = taurochenodeoxycholic acid
What percentage of bile salts secreted into the intestine are reabsorbed as mixed bile salts/acids?
What is the job of a resin during cholsterol control?
to block reabsorption of bile salts so the liver has to use more cholesterol to synthesize more bile salts for use
What is cholelithiasis?
Gallstones from cholesterol deposition
not enough bile acids to help solubilize the bile salts, overproduction of bile salts, too much cholesterol