Pharmacology Exam 3

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Author:
Rx2013
ID:
44284
Filename:
Pharmacology Exam 3
Updated:
2010-10-22 22:07:35
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Nervous System
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Nervous System
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  1. Sympathetic Activation on HR
    increases
  2. Sympathetic Activation on BP
    increases
  3. Sympathetic Activation on BG
    increases
  4. Sympathetic Activation on pupil diameter
    increases
  5. Sympathetic Activation on cardiac contractility
    increases
  6. Sympathetic Activation on GI motility
    decreases
  7. Sympathetic Activation on Bronchi
    dilation
  8. Parasympathetic activation effect on HR
    decrease
  9. Parasympathetic activation effect on pupil diameter
    decrease
  10. Parasympathetic activation effect on GI motility
    increase
  11. Parasympathetic activation effect on bronchi
    constriction
  12. Parasympathetic effect on saliva
    watery
  13. sympathetic effect on saliva
    thick
  14. Metyrosine
    inhibits tyrosine hydroxylase
  15. carbidopa
    inhibits dopamine production peripherally
  16. reserpine
    inhibits VMAT transporter storage of NE into vesicles
  17. Cocaine
    inhibits reuptake of NE
  18. TCAs
    inhibits reuptake of NE
  19. Amphetamine
    increases dopamine concentrations in nerve terminals
  20. selegiline
    inhibits MAO, decreasing degredation of catecholamines
  21. Bretylium and guanethidine
    inhibit vesicle protiens that help release NE
  22. Patients lacking pseudocholinesterse
    have longer effects of succinylcholine
  23. Hemicholinium
    inhibits the influx of choline
  24. vesamicol
    inhibits the uptake of ACH into vesicles
  25. Botulinium toxin
    inhibits SNAPs for vesicle formation
  26. Latrotoxin
    • venom of black widow spider
    • stimulates ACH release
  27. Neostigmine
    used for myasthenia gravis
  28. Hexamethonium
    anti HTN crisis
  29. Depolarizing drugs (ACH)
    • nicotine
    • stimulates blockade at high doses
  30. Competitive ACH blockers
    • trimethaphane
    • TEA
    • Mecamylamine (low dose)
  31. Non-competitive blockers
    • hexamethonium
    • mecamylamine (high dose)
  32. predominant tone determined by sympathetics
    • arteries
    • veins
    • sweat glands
  33. predominant tone determined by parasympathetics
    • heart
    • eye
    • GI
    • bladder
    • salivary glands
  34. effect of ganglionic blockade on arteries and viens
    dilation, hypotention
  35. effect of ganglionic blockade on iris
    mydriasis
  36. effect of ganglionic blockade on ciliary muscles
    cycloplegia
  37. effect of ganglionic blockade on GI tract
    constipation
  38. effect of ganglionic blockade on bladder
    urinary retention
  39. effect of ganglionic blockade on salivary glands
    xerostomia
  40. effect of ganglionic blockade on sweat glands
    anhidrosis
  41. decrease peripheral resistance
    increase HR
    B2 adrinergic drugs
  42. increase peripheral resistance
    decrease HR
    alpha adrenergic drugs

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