Glucose-6-Phosphate Dehydrogenase Deficiency
- Lack of glucose-6-phosphate dehydrogenase (enzyme present in RBCs) in the blood, which can cause hemolytic anemia
- An inherited disorder (X linked)
- Most common in African American males, also seen in persons from the Mediterranean & Asia
- Mild cases: only older RBCs are affected.
- Severe cases: RBC hemolysis is more serious & affects younger cells too