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What is a nuclephile
-Any negative ion or neutral molecule that has at least one unshared electron pair
-Reagent that seeks a positive center
-Donates an electron pair to the substrate
- -NH2, RO-, HO-,
- tert-butoxide is a very useful sterically hindered base
Substrates are R-X where X is what?
- Leaving group, normally:
- Halide I->Br->Cl->F-
Sn1 reactions proceed faster in what type of solvents
SN2 reactions proceed faster in what type of substances?
Polar Aprotic Solvent
Inversion refers to what in an SN2 reaction
The Carbon atom has its configuration turned inside out