med agents cancerB

The flashcards below were created by user krug0043 on FreezingBlue Flashcards.

  1. 6 classes of hormonal therapy for CA
    • SERMS
    • Aromatase Inhibitors
    • Progestins and Androgens
    • Gonadotropin-Releasing Hormone Analogs
    • Antiandrogens
    • Somatostatin Analogs
  2. 4 classes of differentiation agents for CA
    • Retinoids
    • Histone Deacetylase (HDAC) Inhibitors
    • DNA Methyltransferase (DNMT) Inhibitors
    • Arsenic Trioxide
  3. 4 Classes of angiogenesis inhibitors for CA
    • Endogenous inhibitors
    • VEGFR inhibitors
    • Integrin inhibitors (alphavB3)
    • Matrix metalloproteinase inhibitors (MMPI)
  4. Classes and subclasses of protein processing inhibitors for CA
    • Post-Translational Modifications
    • Tyr kinase inhibitors (EGFR, BCR-ABL, VEGF)
    • Ser/Thr kinase inhibitors (mTOR)
    • Farnesyl transferase inhibitors (FTIs)

    • Protein Degradation
    • Proteasome inhibitors
    • Matrix metalloprotease inhibitors (MMPIs)
  5. 4 Classes of Biotherapeutics for CA
    • Enzymes
    • Mabs
    • Cytokines (interferons, interleukins, hematopoietic growth factors)
    • Vaccines
  6. 7 Miscellaneous Classes of Cancer Drugs
    • Photosensitizers
    • Hydroxyurea
    • Amifostine
    • Bisphosphonates
    • COX Inhibitors
    • Pgp Inhibitors
    • Unknown mechanism
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    Retinoids (tretinoin)
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    misc retinoids
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    Pharmacophore model for HDAC inhibitors

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  10. What element do HDAC inhibitors chelate?
    Zinc
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    SERMs
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    SERMs
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    SERM (tamoxifene)
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    aromatase inhibitor
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    protease inhibitor
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    antiandrogen
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    DNA interactive agent
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    differentiating agent
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    DNA interactive agent
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    tubulin binding agent
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    antimetabolite
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    kinase inhibitor
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    antiestrogen
  24. Rate limiting enzyme in estradiol biosynthesis.
    Aromatase
  25. MOA of arsenic trioxide
    generates reactive oxygen species leading to cell death
  26. 3 Classes of tyrosine kinase inhibitors
    • EGFR
    • BCR-ABL
    • VEGF
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    Integren antagonist (AvB3)
Author:
krug0043
ID:
44783
Card Set:
med agents cancerB
Updated:
2010-10-26 12:16:02
Tags:
med agents test
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Description:
third med agents test. second test on cancer. the other file i named med agents test 3 is acutall the fourth med agents test on microbials.
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