med agents cancerB

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Author:
krug0043
ID:
44783
Filename:
med agents cancerB
Updated:
2010-10-26 08:16:02
Tags:
med agents test
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Description:
third med agents test. second test on cancer. the other file i named med agents test 3 is acutall the fourth med agents test on microbials.
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  1. 6 classes of hormonal therapy for CA
    • SERMS
    • Aromatase Inhibitors
    • Progestins and Androgens
    • Gonadotropin-Releasing Hormone Analogs
    • Antiandrogens
    • Somatostatin Analogs
  2. 4 classes of differentiation agents for CA
    • Retinoids
    • Histone Deacetylase (HDAC) Inhibitors
    • DNA Methyltransferase (DNMT) Inhibitors
    • Arsenic Trioxide
  3. 4 Classes of angiogenesis inhibitors for CA
    • Endogenous inhibitors
    • VEGFR inhibitors
    • Integrin inhibitors (alphavB3)
    • Matrix metalloproteinase inhibitors (MMPI)
  4. Classes and subclasses of protein processing inhibitors for CA
    • Post-Translational Modifications
    • Tyr kinase inhibitors (EGFR, BCR-ABL, VEGF)
    • Ser/Thr kinase inhibitors (mTOR)
    • Farnesyl transferase inhibitors (FTIs)

    • Protein Degradation
    • Proteasome inhibitors
    • Matrix metalloprotease inhibitors (MMPIs)
  5. 4 Classes of Biotherapeutics for CA
    • Enzymes
    • Mabs
    • Cytokines (interferons, interleukins, hematopoietic growth factors)
    • Vaccines
  6. 7 Miscellaneous Classes of Cancer Drugs
    • Photosensitizers
    • Hydroxyurea
    • Amifostine
    • Bisphosphonates
    • COX Inhibitors
    • Pgp Inhibitors
    • Unknown mechanism
  7. Retinoids (tretinoin)
  8. misc retinoids
  9. Pharmacophore model for HDAC inhibitors

  10. What element do HDAC inhibitors chelate?
    Zinc
  11. SERMs
  12. SERMs
  13. SERM (tamoxifene)
  14. aromatase inhibitor
  15. protease inhibitor
  16. antiandrogen
  17. DNA interactive agent
  18. differentiating agent
  19. DNA interactive agent
  20. tubulin binding agent
  21. antimetabolite
  22. kinase inhibitor
  23. antiestrogen
  24. Rate limiting enzyme in estradiol biosynthesis.
    Aromatase
  25. MOA of arsenic trioxide
    generates reactive oxygen species leading to cell death
  26. 3 Classes of tyrosine kinase inhibitors
    • EGFR
    • BCR-ABL
    • VEGF
  27. Integren antagonist (AvB3)

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