Dosage forms test1 stability 2
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Release of water of hydration from crystal hydrate
Particles clumping is due to
Dissolution of solid upon uptake of atmospheric moisture.
T/F Drugs are chemically more stable in liquid state.
Uptake of water by solid drug accelerate chemical degradation
Stressing the solid with high humidity tests for
Drugs with high vapor pressure may volatize thru or in container
flavorants, cosolvents, nitroglycerin (can pass out of container)
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