Card Set Information
What is immunity?
Ability of the body to defend against infection agents, foreign cells, abnormal cells
What are the immunity system's three lines of defense?
Innate immune system
Acquired or Adaptive Immunity
What is a physical barrier? give an example
The immunity system's first line of defense. skin, mucus, tears
What are interferons?
serve as signals during immune response
What are anitmicrobial agents?
Act to deter or destroy microorganisms
What is lactoferrin and transferrin and where are is each found?
They reduce iron so bacteria can't grow (bacteria needs iron)
Lactoferrin- milk saliva, mucus, tears
What is a complement?
A family of more than 20 proteins in the blood serum.
How do complements work?
Coat pathogen so phagocytes can ingulf
lyse cell wall
Release substances like histamine that increase inflamation
Attract lymphocytes to the infection site
What do phagocytic cells do?
Engulf and devour pathogen
uses lysozymes, nucleases, proteases etc
What are the two types of phagocytic cells?
Stationary (macrophages) engulf cells
What are the two types of leukocytes?
Neutrophils- best on bacteria
Monocytes - mobile phase of macrophage
What are the 3 nonphagocytic cells?
Basophils- Inflammation and allergies
Eosinophils- phagocytic and used against parasitic worms
Lymphocytes- acquired immunity
What are natural killer cells?
Non-phagocytic cells that kill infected cells
What are lymphocytes?
T, B and NK cells and are circulated in lymphatic system and blood
What are B-lymphocytes?
Made in bone marrow
Plasma cellsm (effector)
What is the Major Histocompatibility Complex (MHC)?
Body cell antigens that identify the cells of the body as a self.
Activates B and T cells
What are antibodies (immunoglobulins)?
Made of 2 heavy and 2 light polypeptide chains
What are the immune system disorders?