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what is the general structure of porphyrin?
- four pyrrole rings (A,B,C,D) connected by methenyl (-HC=) bridges
- eight side chains, two per pyrrole unit (R1-R8)
What will make porphyrin compund colorless?
what happens to the name?
- a reduction of the methenyl bridges to methylene bridges (-CH2-)
- colorless tetrapyrroles end in suffix -ogen
what are pophyrias caused by?
a deficiency in any of the heme biosynthetic enzymes (except ALA-S)