Lecture 53.txt

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Author:
cjharmon311
ID:
45557
Filename:
Lecture 53.txt
Updated:
2010-10-28 19:57:00
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Porphyrin Biosynthesis
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Description:
Porphyrin Biosynthesis
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  1. what is the general structure of porphyrin?
    • four pyrrole rings (A,B,C,D) connected by methenyl (-HC=) bridges
    • eight side chains, two per pyrrole unit (R1-R8)
  2. What will make porphyrin compund colorless?
    what happens to the name?
    • a reduction of the methenyl bridges to methylene bridges (-CH2-)
    • colorless tetrapyrroles end in suffix -ogen
  3. what are pophyrias caused by?
    a deficiency in any of the heme biosynthetic enzymes (except ALA-S)

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