AP5

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felizdiaz
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47019
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AP5
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2010-11-03 12:16:59
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  1. FIVE FUNCTIONS OF HORMONE SYSTEM
    • 1. DIFFERENTIATION OF REPRODUCTIVE AND CNS OF FETUS
    • 2. GROWTH OF KIDS AND TEENS
    • 3. MAKE AND FEMALE ORGANS
    • 4. MAINTAIN INTERNAL ENVIRONMENT
    • 5. EMERGENCY DEMANDS
  2. LIPID SOLUBLE HORMONES
    • ANDROGENS
    • ESTROGENS
    • PROGESTINS
    • GLUCOCORTICOIDS
    • MINERALOCARTICOIDS
    • THYROID
  3. POSTERIOR PIT
    • GET INFO (VIA NERVES) AND HOMORONES FROM HYPOTHALAMUS
    • STORES ADH AND OXYTOCIN
  4. ANTEROIR PIT
    • SLOWER RELEASE OF HORMONES CAUSE MUST RECIEVE RELEASING HORMONE FROM HYPOTHALMUS
    • LIKE CORTICOTROPIN RELEASING HORMONE
    • THYROTPOIN RELEASING
    • GROWTH HORMONE RELEASING
    • GONADOTROPIN RELEASE
    • THEN IT CAN RELEASE THE HORMONE
  5. ANTERIOR PIT HORMONES TO KNOW
    • CORTOCOTROPIN - ACTH
    • SOMATOMAMMOTROPINS- GROWTH HORMONE(BODY) AND PROLACTIN(BREAST)
    • GLYCOPROTIENS-TSH
  6. THYROID GLAND
    • CELL TYPES
    • FOLLICULAR CELL-MAKE THYROID HORMONE T3 +T4 (STORED IN COLLOID CELL)
    • PARAFOLLICULAR- MAKE CALCITONIN (FOR CA++)
  7. PARATHYROID GLANDS
    • IN THYROID GLAND (4 OF THEM)
    • MAKE PTH (TO INCREASE BLOOD CA) ANTAGONIT OF CALCITONIN
    • EFFECTS BONE, GI, KIDNEY
    • LOW MG AND NORM CA INCREASE PTH
    • LOW MAG AND LOW CA LOWER PTH ON TEST
    • LOW CA INCREASE PTH
  8. PANCREAS
    • ISLET OF LANGERHANS
    • ALPHA CELL-MAKE GLUCAGON (INCREASE BS)
    • BETA CELL- MAKE INSULIN (LOWER BS)
    • DELTA CELL- SOMATOSTATIN (REGULATE A+B CELL OF PAN), GASTRIN (STOMACH ACID)
    • F CELLS- PANCREATIC POLYPEPTIDE

    IS MOSTLY PNS ORGAN
  9. ADRENAL CORTEX
    • OUTTER LAYER OF ADRENALS
    • NO INNERVATION ALL HORMONES (ACTH)
    • MAKES
    • GLUCOCORTICOID (CORTISOL)
    • MINERALOCORTICOID (ALDOSTERONE)
    • ADRENAL ESTROGENS AND ANDROGEN
  10. GLUCOCORTICOIDS
    • EFFECT CARB META
    • GLUCOSE BLOOD LEVELS
    • ANTIINFLAMM
    • SUPRESS ANTIINFLAM RESPONSE
    • SLOWS GROWTH
    • INFLUNCE AWARENESS AND SLEEP HABIT
    • UP EATING
    • UP ERTHROCYTE FORMATION
    • CORTISOL
  11. MINERALCORTICOODS
    • AFFECT ION TRANSPORT
    • UP NA PUMP OF EPITHELIAL CELL
    • NA K AND WATER RETENTION
    • REGULATED BY REINE- ANGIOTENSIN
    • ALDOSTERONE
  12. ESTROGEN AND ANDROGENS
    • ESTORGEN SECRETION IS MINIMAL
    • ANDROGEN IS WEAK BUT IS CONVERT TO TESTOSTERONE IN TISSUE
  13. MECH OF COMMUNICATION
    • AUTOCRINE- IN CELL
    • PARACRINE- LOCAL CELLS
    • ENDOCRINE- REMOTE CELLS
  14. CLASSIFICATIONS OF HORMONES
    • STRUCTURE
    • ORIGIN
    • EFFECTS
    • CHEM COMPOSITION
  15. HOROMONE TRANSPROT
    • WATER SOL ARE FREE AND UNBOUND
    • LIPID SOL ARE BOUND AND NEED CARRIER (PROTEIN LIKE
  16. HOW WATER HORMONES WORK
    • BIND TO CELL SURFACE RECEPTOR
    • G PROTIENS ARE LINKED THEN TO
    • SIGNAL GENERATOR THEN
    • SECOND MESSENGER THEN
    • ACTIVATION OF INTRACELLUAR ENZYME (PROTIEN KINASE A OR C)
    • LEADS TO GENE TRANSCRIPTIONS
  17. SECOND MESSAGERS
    • G PROTEINS
    • cAMP
    • cGMP
    • PHOSHOLIPASE
    • CALCIUM

    IT IS WHAT DOES THE WORK
  18. PHOSPHOLIPASE C ACTIVATION
    • PIP2+ GTP= IP3
    • IR3 RELEASE CA FORM ER
    • CA THEN ACTIVATES IT
  19. cAMP ACTIVATION
    • ATP WITH ADENYL CYCLASE MAKE cAMP
    • THEN cAMP ACTIVATES PKA THAT ACTIVATING OR INHIBITING
    • CARDIAC CELL THEN HOLD CA++ FOR STRONG CONTRACTION OF HEART
    • IF GOES ON TOO LONG LEADS TO AUTODESTRUCTION OF CELL
  20. cGMP ACTIVATION
    • GTP TO cGMP
    • ACTIVATE KINASE
    • LEADS TO ACTIVE OR INHIBITS PROTIENS
    • MOSTLY ACTH = PNS

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