biochem lecture 28
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biochem lecture 28
biochem 28 ex3
desaturation of fatty acids requires _______ and _____________.
cytochrome b5, NADPH-cytochrome b5 reducase.
Fatty acid is activated by attaching to
Oxidation of fatty acid occurs here.
_______ is the transport molecule for fatty acids into the mitochondrial matrix.
Oxidation of palmitate yields _ oxidations and _____ is the final product. Overall yield is ___ ATPs.
B-Oxidation oxidizes _______ fatty acids with ____ number.
odd chain fatty acids produce this.
Alpha-oxidation necessary for metabolism of _____ ____ fatty acid, uses fatty acid ________ which occurs in peroxisomes.
synthesis of fatty acids
Subcellular location- cytosol
acyl carrier- actyl carrier protein
inhibitor- long chain fatty acid acyl CoA
4 step- cond, reduction, dehydrat, reduction
degradation of fatty acid
subcellular location- mitochondria
acyl carrier- CoA
inhibitor- Malonyl CoA
product- acetly coa
4 step- Dehydrogenation, hydration, dehydrog, thiolysis
water soluble lipid based energy : _____ and ______
Acetoacetic acid and B-hydroxybutyric acid
Ketone body production occurs in the
Ketone body formation can be considered an _______ pathway.
ketone body formation stimulated with acetyl-CoA accumulates due to ____ carbohydrate utilization, low level of _______, citrate synthase activity is ___.
Energy for ketone bodies is derived from _______ being converted to acetoacetyl CoA in tissues other than the ____ such as the _____ and muslce.
synthesis of lipids does the following
Increases release of insulin
protein phosphatase activity
inhibits hormone sensitive lipase
and activates acetyl CoA carboxylase (Rate limit enzyme)
degradation of lipids does this
releases glucagon and epinephrine
protein kinase activity
inhibit acetyl coa carboxylase
activate hormone sensitive lipase