MENs

Card Set Information

Author:
SerratYasargil
ID:
49165
Filename:
MENs
Updated:
2010-11-12 16:48:37
Tags:
Multiple Endocrine Neoplasias
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Description:
The Multiple Endocrine Neoplasias
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  1. The
    Multiple Endocrine Neoplasias
    • All are autosomal dominant
    • pheochromocytomas of MEN-2A and -2B are associated with
    • ret protooncogene mutation
  2. MEN-1
    (Wermer's Syndrome)
    • (3ps)
    • parathyroid tumors (GH, prolactin)
    • pancreatic endocrine tumors
    • -Zollinger-Ellison Syndrome
    • ---insulinomas
    • ---vip'omas
    • ---glucagonomas (rare)
  3. MEN-2A
    (Sipple's Syndrome)
    • (2p's)
    • Medullary Thyroid Carcinoma (secretes calcitonin)
    • pheochromocytoma
    • parathyroid tumors
  4. MEN-2B
    • (1 p)
    • Medullary thyroid carcinoma (secretes calcitonin)
    • Mucosal Neuroma's (oral/intestinal ganglioneuromatosis - associated with marfanoid habitus)
    • pheochromocytoma

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