Restrictive Resp. disorders

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Restrictive Resp. disorders
2010-11-14 00:36:47

restrictive resp disorders exam3
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  1. How are respiratory disorders characterized?
    Decreased compliance (expansion/elasticity) of the lungs or chest wall or both
  2. What can be some causes of restrictive resp. disorders?
    • CNS: head injury, tumor, stroke, narcotic or barbiurate OD
    • Neuromuscular disorders: Guillian-Barre Syndrome, Amyotropic Lateral Sclerosis, Myasthenia Gravis, Musculr Dystrophy
    • Chest wall orgin: chest trauma (flail chest, fractured ribs), Pickwickian syndrome (pt. morbidly obese and can't expand lungs), Kyphoscoliosis
    • Pleural disorders: pleural effusion, pleurisy, pneumothorax
    • lung parenchymal disorders: atelectasis, pneumonia, intestitial lung disease, ARDS (acute resp. distress syndrome)
  3. What does a PFT show for restrictive resp. disorders?
    • -Decr. inspiratory values
    • -reduced vital capacity
    • -reduced TLC total lung capacity
  4. What features do all interstitial pulmonary disorders have in common?
    They affect the alveoli, blood vessels, and surrounding support tissue of the lungs rather than the airways, they are restrictive
  5. What happens to the alveoli w/ intersititial pulm. disorders?
    alveoli becomes inflammed and leads to pulmonary fibrosis, or scarring that becomes stiff, and noncompliant w/ poor recoil and expanision and poor gas exchange
  6. What is the most common sx of interstitial pulmonary disorders?
    exertional dyspnea. you may also hear fine crackles and see rapid shallow resps, and clubbing
  7. What are some labs/diagnostics typical of interstitial pulm disease?
    • -ABG's show hypoxia
    • -CXR shows characteristic infiltrative patterns
  8. Describe cor pulmonale
    cor pulmonale is a result of pulm HTN, as the heart can no longer pump efficiently against the stiff lung, it leads to L sided heart failure and death
  9. What is interstitial pulm. disorders typically caused by? What are they?
    • caused by occupational exposure
    • 1) pneumoconioses- inhalation of inorganic dust and particulate matter (asbestos, silicosis, coal workers "black lung" disease) has a poor prognosis
    • 2)hypersensitivity pneumonitis (exposure to cotton dust, sugar cane fiber)
  10. What is the goal of care in regards to interstitial pulm disorders?
    reduce inflammatory response, prevent disease progression, manage dyspnea and provide supportive care late in the disease
  11. What are some interventions for the pt. w/ interstitial pulm disease?
    • -corticosteroids and other immunosuppressants (most common med)
    • -preventative teaching to environmental hazards
    • -smoking cessation
    • -vaccines
    • -adequate fluids
    • -home O2
    • -hospice care...reduction of dyspnea by providing morphine: oral, parenteral or nebulized
  12. What is Sarcoidosis?
    • -A restrictive resp disorder of unknown cause that mostly affects the lungs.
    • -involves a autoimmune response- T-lymphocytes incr. and cause damage to alveolar cells . Normally T-lymphocytes are protective but w/ Sarcoidosis they form granulomas on the alveoli that cause fibrosis that reduces lung compliance and gas exchange...cor pulmonale often results
  13. How is Sarcoidosis manifested?
    • -enlarged lymph nodes in the hilar area of the lungs
    • -lung infiltrate on CXR (the first indication of the disease may be an abnormal CXR in an otherwise healthy pt.)
    • -cough, dyspnea, hemoptysis and chest discomfort
  14. How is Sarcoidosis treated?
    • -The goal of therapy is to lessen the s/sx and prevent fibrosis.
    • -Corticosteroids for severe manifestations, hepatic insufficiency, cardiac dysrhythmias, CNS involvement or disfiguring skin lesions
    • -Immune modifiers (e.g. chloroquine, indomethacin, azathiaprine, methotrexate)
    • -If asymptomatic and normal PFT's- no treatment.
  15. What is the nursing care for a pt. w/ Scardosis?
    • -Teach about corticosteroids: do not stop abruptly, take w/ food or milk to minimize GI upset, limit Na and incr. K
    • -symptom relief of inflammatory symptoms (arthralgias, eye inflammation)
  16. What is pneumonia?
    Pneumonia= an inflammatory process that results in edema of ung tissue and movement of fluid into the alveoli, causing hypoxemia

    The normal protective mechanisms are overcome (warming, filtraionand humididfication of inspired air, closure of epitlottis over trachea, cough reflex, mucociliary movement, secretion of Immunoglobin A, alveolar macrophages)
  17. What are the 2 types of pneumonia?
    • 1) community aquired (CAP), most common streptococcus pneumonia (gram +) treated w/ PCN or cephlosporins
    • 2) Hospital-aquired (nosocomial), most common staphylococcus areus (gram +) treated w/vanco, zosyn, levaquin

    Nonsosomial has a high mortality rate: mechanical ventilation incr. risk, contaminated respiratory equipment, immunosuppression and general debilitaion.
  18. How can pneumonia occur in the lungs? Which segments
    • 1) Lobar- w/ consolidation ina segment or entire lobe
    • 2) bronchopneumonia- w/ diffusely scattered patches around the bronchi
  19. What is the general patho of pneumonia?
    • -fibrin and edema of inflammation stiffen the lung= decr. lung compliance and vital capicity
    • -decr. producting of surfactant leads to atelectasis
    • -venous blood passes thru underventilated areas, leading to hypoxemia
    • -tissue necrosis can result when multiplying organisms from abscesses that perforate bronchial wall
    • -can lead to sepsis
  20. Discuss Bacterial Pneumonia
    • -presents w/ rapid onset of shaking, fever, cough of rust-colored purulent sputum
    • -pleuritic pain common
    • -fine crackles over affected lobe
    • -signs of pulm. consolidation (dullness to percussionincr. fremitus, bronchial BS)
  21. Discuss mycoplasma and viral pneumonias
    • -have gradual and atypical presentations d/t interstitial rather than alveolar inflammation
    • -HA, myalgias, fatigue sore throat, n&v, diarrhea, crackles, dry hacking, nonproductive cough
    • -elderly pts may present w/ confusion or stupor as the primary finding
    • -typical in younger population aka "walking pneumonia"...treated w/ azithromycin or erythromycin (typical PCN or cephlosporins won't work)
  22. Discuss sputum color w/ type of pneumonia
    • 1) bacterial- rust color
    • 2) pseudomonis- green
    • 3) staph- yellow
  23. On a CXR what does lobar or segmental consolidation suggest?
    • 1)Pneumococcus or
    • 2) Klebsiella
  24. On a CXR what does diffuse infiltrates suggest?
    • 1)viral
    • 2)legionella
    • 3)fungal
  25. On a CXR what does a cavity shadow suggest?
    Necrotizing infection w/ S. aureus, gram neg bacteria or mycobacterium TB
  26. W/ CAP 30% of pt.s show what?
    pleural effusion
  27. When do you want to collect a sputum culture for suspected pneumonia?
    before AB therapy is started
  28. what will a pt's ABG's look like if they have hypoxia?
    low O2 levels
  29. What will a pt's WBC look like w/ PNA?
    • >15,000 w/ presence of bands (immature neutrophils)
    • unless they are elderly/immunocompromised and can't muster up a rxn and show elevated counts
  30. How is PNA treated?
    • -emperic AB
    • -O2 PRN
    • -analgesics, antipyretics
    • -rest
    • -postural drainage, chest physiotherapy to mobolize secretions
    • -FLUIDS! (IV or oral) at least 3000 mL/day unless contraindicated
    • -nutritional support of at least 1,500 cal/day, small frequent meals
    • -Amantadine and Rimantidine for Influenza A Virus. During influenza epidemics, recommended as chemoprophylaxis for nursing home pts, immunocompromised or unvaccinated pts
    • -vaccines!
  31. What is TB?
    • -A restrictive resp. disorder that is highly communicable caused by Mycobacterium tuberculosis, a gram-pos acid fast bacillus
    • -TB usually involves the lungs but may also occur in the larynx, kidneys, bones, adrenal glands, lymph nodes, meninges...can be disseminated throughout entire body
    • -significant public health concern d/t incr. numbers of impoverished/homeless perosns and multi-drug resistant strains
  32. How is TB transmitted?
    • airborne transmission-infected person coughs, sneezes etc, droplet nuclei inhaled by others, TB multiplies freely when it reaches a susceptible site
    • -non-specific pneumonitis occurs and resolves in healthy individuals but 5-15% aquire the disease
    • -cell mediated immunity develops in 2-10 wks, resulting in a positive TB test
  33. What is the patho of TB?
    • -Granulomatous inflammation created by the tubercle bacillus in the lung becomes surrounded by collagen, fibroblasts and lymphocytes
    • -Necrosis ("caseation" cheese like) occurs in the center of the lesion. "Ghon tubercle" shows on CXR and is the primary lesion...necrotic areas may calcify and liquify
    • -calcified "Ghon complex" may form and enter a latent period, then can be reactivated if hosts immune mechanisms are impaired
    • -if liquefacation occurs, the liquid empties into a bronchus and the evacuated area becomes a cavity.
    • -bacilli continue to grow in the necrotic cavity wall and spreade via tracheobronchial lymph nodes to new areas of the lung
  34. What are the clinical manifestations of TB?
    • -may be asymptomatic in early stage
    • -fatigue, malaise, anorexia, wt. loss, low-grade fevers (fever spike tends to happen in the afternoon), night sweats
    • -wt.losslater in disease
    • -frequent cough of purulent sputum
    • -dull or tight chest pain
  35. What are the diagnostic findings in TB?
    • -positive smear for acid-fast bacilli
    • -confirmation by sputum culture (best collected in AM)- can identify in 1-3 wks (slow growing)
    • -repeat cultures after tx, should be neg. after 3 months
    • -cavitation and calcified lesions may be seen on CXR but aren't specific enough to be sole basis for diagnosis
    • -TB skin test
  36. Discuss the medical tx for TB
    • -duration of tx is 6-12 mo.
    • -Directly Observed Therapy (DOT) is recommended for patients at risk for noncompliance
    • -resp. isolation until 3 neg smears
    • -negative pressure, UV light directed at upper part of room, HEPA (high efficency particulate air) filter
    • -evaulation of susceptible family members
    • -major s/e of INH, RIF and PZI is hepatitis, monitor LFTs
  37. Discuss Isoniazid (INH), a first line drug for treating TB
    • -interferes w/ DNA metabolism of tubercle bacillus
    • -s/e= hepatotoxicity (monitor LFTs) peripheral neuritis, hypersensitivity (skin rash, arthralgia, fever), optic neuritis, vit B6 neuritis, may inhibit metabolism of phenytoin, carbamazepine and warfarin
    • -nursing considerations: pyridixine (Vit. B6) supplements needed during high-dose therapy (Vit B6 can cause terrible nightmares)
    • -INH is used as single prophylactic agent for individuals when PPD converts positive
    • -taken on empty stomach
  38. Discuss Rifampin (RIF), a first line drug for treating TB
    • -has broad spectrum effects, inhibits RNA polymerase of tuvercle bacillus
    • -s/e: hepatotoxicity (monitor LFTs), febrile rxn, GI upset, peripheral neuropathy, may enhance elimination of theophylline, steroids, oral hypoglycemics, warfarin
    • -nursing considerations: most commonly used w/ INH, low incidence of s/e
    • -suppresses birth control pills
    • -causes orange discoloration of body secretions/urine. teach pt. to continue taking med
  39. What are some common drugs for the 2nd line of tx for TB?
    cipro and levaquin
  40. What is SARS?
    • Severe Acute Respiratory Distress Syndrome, an atypical pneumonia first identified in China in 2002
    • -caused by SARS-CoV which is widespread among cattle, pigs, rodents, cats, dogs- virus mutates and transfers to humans but not human to human
    • -s/sx range from simple febile resp. illness to severe pneumonia and death
    • -incubation period= 2-7 days but can be as long as 10 days
    • -viral shedding peaks in resp. specimens and stools at around day 10 after the onset of the clinical illness (unlike other viral illnesses where the contagious period is early in the disease process)
  41. What is the assessmnet findings and diagnosis for SARS?
    • -fever over 100.4, HA, arthralgias, fatigue, sore throat, N/V, diarrhea
    • -in 2-4 days nonproductive cough and difficulty breathing, SOB, low O2 sats, and cyanosis =more severe illness!
    • -lab tests show lyphopenia, mild thrombocytopenia, elevated liver enzymes, cultures to r/o other causes
    • -CXR may be normal in first wks of illness an dlater have an ARDS type picture...these pts probably need to be on a vent
    • -viral culture may or may not isolate SARS-CoV form nasopharyngeal swab during first week, but after week 1 of illness get a stool specimen
    • -presence of antibody more than 21 days after sx onset
  42. What is the collaberative management for SARS
    • -supportive, no effective tx known
    • -steroids and antivirals-AB may be considered for concurrent CAP
    • -Infection control:
    • -pt's w/ over a 100.4 fever or resp. sx should be given a surgical mask and asked about travel hx
    • -if suspected SARS put pt in private room and notify infection control
    • -airborne and contact precautions in neg. pressure room, N-95, gown and gloves
    • -follow up CXR after 1 week after discharge
    • -if at home pts should stay home for 10 days after resolution of fever, in seperate bedroom, bathroom, own eating utensils and linen (bc SARS shed in stool)