midterm-3.txt

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Author:
janejingy
ID:
49899
Filename:
midterm-3.txt
Updated:
2010-11-16 08:30:58
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pharmacology
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pharmacology
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  1. What are the functions of the kidney?
    • Excrete most of the end products of body metabolism
    • Control the concentration of most of the constituents of body fluid, a constant blood volume and amounts of solutes in the blood
    • Maintain the pressure of blood flow
  2. Agents Affecting the Proximal Tubule
    Acetazolamide (Diamox?): emergency situation, pressure in the eye
  3. Agents Affecting the Loop of Henle
    Furosemide (Lasix?): oral
  4. Agents Affecting the Distal Tubule
    • Hydrochlorothiazide (Hydrodiuril?, Dyazide?, Maxzide?)
    • Triamterene (Dyazide?, Maxzide?)
    • Metolazone (Zaroxolyn?)
  5. Side effects of Diuretic
    • Orthostatic Hypotension: older people tends to have more
    • Hyperglycemia
    • Potassium Loss
  6. What is spironolactone?
    • Spironolactone (Aldactone?)
    • Aldosterone Antagonist, Aldosterone causes Na and fluid retention.
    • used in conjunction with other diuretics to prevent potassium loss.
    • Few side effects, mainly elevated potassium levels.
  7. What is triamterene?
    • Dyazide?, Maxzide?
    • Acts directly on the distal convoluted tubules to cause diuresis while inhibiting potassium excretion.
    • used in conjunction with other diuretics to prevent potassium loss.
  8. How do ACE inhibitors work? What conditions are they used to treat?
    • Hypertension
    • Congestive Heart Failure
    • Post MI
  9. How do ARB��s work? What conditions are they used to treat?
    • Angiotensin II Receptor Antagonists
    • Hypertension
    • Congestive Heart Failure
    • Post MI
    • Diabetic nephropathy
  10. How do direct rennin inhibitors work?
    • impacts the rennin/angiotensin system.
    • Aliskiren (Tekturna?): Hypertension
  11. Patients taking which of the following drugs might also need to take a potassium supplement? Furosemide? Hydrochlorothiazide? Maxzide or Dyazide? Spironolactone? ACE Inhibitors? Angiotensin II Antagonists? Direct Renin Inhibitors?
    • Dyazide?, Maxzide?: Hyperkalemia
    • ACE Inhibitors: Hyperkalemia
    • ARB��s : has little effect on potassium concentrations.
    • Aliskiren (Tekturna?): Hyperkalemia

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