Multisystem

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Author:
cathy4xo
ID:
50396
Filename:
Multisystem
Updated:
2010-11-18 05:26:46
Tags:
Multisystem
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Description:
Multisystem
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  1. Describe the symptoms/signs of SLE.
    • Malar/discoid rash
    • Photosensitivity- exposure to UV light causes a rash
    • Oral ulcers (including nasopharyngeal ulcers)
    • Arthritis
    • Serositis – pericarditis or pleuritis or evidence of a pericardial effusion
    • Renal disorder – proteinuria > 0.5g/d or 3+ or cellular casts
    • Neurologic disorder – seizures or psychosis
    • Haematologic disorder - haemolytic anaemia or leukopenia or lymphopenia or thrombocytopenia
    • Immunologic disorder – Anti-dsDNA, anti-Sm and/or anti-phospholipid
    • Antinuclear antibodies - an abnormal titre of ANA
  2. Name 5 drugs that can cause SLE.
    • Hydralazine
    • Isoniazid
    • Methyldopa
    • Quinidine
    • Interferon-a
  3. What is rheumatoid factor?
    • Rheumatoid factors are autoantibodies of the IgG,
    • IgA or IgM class which react with the Fc portion of IgG
  4. What are the medications for SLE? (name 4)
    • Prednisone
    • Rituximab
    • Cyclophosphamide
    • Anti-malarials

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