PBD 4 Depression

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Author:
swynocker
ID:
51045
Filename:
PBD 4 Depression
Updated:
2010-11-22 00:09:20
Tags:
PBD Depression
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Description:
PBD 4 Depression
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  1. For depression you must have _ symtoms for _ weeks
    • 5 symptoms
    • 2 weeks
  2. You can not have drug depression, reactive depression, illness, _____ or Hallucinations, or _____ ____.
    • Delusions
    • Organic factors
  3. Risk factors for unipolar
    • 5-20% incidence in women (most likely)
    • greater risk with family
  4. Risk factors bipolar
    • 1.5% world wide
    • 10% schizo
    • 80% mono
    • Same male:female
  5. Atypical are ____ and _____
    Melancholic are ____ and _____
    • Hypersomnia, overeating
    • Insomnia, anorexia
  6. Bipolar contains depression and ___
    mania
  7. Monoamine def. theory
    • most Anti-dep increase 5HT and NE level
    • evidence less 5HT turnover in suicide
    • tryptophan can improve depression
  8. Suicide victims with major depression have increased
    • 5HT1A somatodendritic autorecepts
    • 5HT2 postsynaptic receptors
  9. Neurokinin hypothesis
    defect in Substance P or neurokinin 1 receptors
  10. Neuroendocrine factors such as hyptothalamic-pituitary-adrenal-axis and hyptothalamic-pit-thryoid axis are what?
    • a) exhibit cortisol hypersecretion
    • b) hypothyroidism, T3 or TRH improve sumptoms
  11. In major depression peopel sleep less in _____ and more in ____
    • latency
    • REM

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