pathogenic micro.txt

The flashcards below were created by user scharmch on FreezingBlue Flashcards.

  1. what are some gram positive rods that are in CMN group? and what are the distictive cell wall components?
    • Mycobacterium/corynebacterium/nocardia
    • the unusual cell wall component are
    • myolic acid
    • cord factor
    • arabinoglactan
  2. what is the difference in the myolic acid of the 3 bacteria in CMN group?
    • mycobacteria had the longest chanin and strongly acid fast
    • nocardia had the intermediate chain and weakly acid fast
    • corynebacteria has the shortest chain and not acid fast
  3. what are the two categories that corynebacterium falls under?
    pathogenic ( C.diphtheriae) non.pathogenic ( opportunistic and part of common microflora C.jeikeium )
  4. what are some characteristics of Corynebacteria
    • gram positive
    • peliomorphic
    • non.spore forming
    • metamprphic (methylene blue stain)
    • not acid fast
    • facultative anaerobe
    • enhanced by Co2
    • catalase +
    • grows waxy
    • ferments carbs to lactic acid
  5. what are some pathogenic factors associated with corynebacterium
    • cord factor
    • exotoxin ( result in phage conversion)
    • two component Toxin
    • potent inhibitor of protein synthesis
    • ADP ribosylation
  6. what are some toxin's associated with C.diphtherea
    • Type 3 toxin
    • A/b subunit toxin
    • .A subunit inhibits interacellular target
    • .b subunit mediate binding to target cell and internallization

    ** toxin action in C.diphtherea inactivate elongation factor 2 preventing protein sysnethis by ribsome
  7. what are some factors involved in pathogenisis
    • it is localized infection to tonsils and orpharynx and spread to larynx and trachea
    • sypm 2.5 days
    • fever
    • obstruction of airways

    ** common microflora
  8. what media does C.diphterease reduce and what color colonies are produced?
    it reduces CTA to produce black colonies
  9. what are some diagnostic ways ?
    • ELK test
    • Toxin test ( vivo test is animal ) vitro test (PCR)
  10. how does C.diphtrea spread ? what is the host? and where is it usually localized to ?
    • it is transmitted by aerosal droplet, and also carried by asymptomatic carriers
    • and in healthy is localized to oropharynx.
  11. what types of immunizations are present?
    passive and active(toxoid)
  12. what are some ways to treat C.diphtereae?
    • Antitoxin
    • penecilin G(erythromycin)
    • active passive immunization
Card Set:
pathogenic micro.txt
2009-10-26 00:16:49

Gram positive rod
Show Answers: