n101.test-3.pharm.diabetes.txt

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digver
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51877
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n101.test-3.pharm.diabetes.txt
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2010-11-29 15:48:53
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N101 test3 pharmacology diabetes
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N101 diabetes pharmacology for test 3
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  1. What are signs of hypoglycemia?
    • Tachycardia
    • Confusion
    • Sweating
    • Drowsiness
  2. List (3) rapid acting insulins.
    • insulin aspart (NovoLog)
    • insulin glulisine (Apidra)
    • insulin lispro (Humalog)
  3. List (2) short acting insulins.
    • insulin regular (Humulin R)
    • insulin regular (Novolin R)
  4. List (2) intermediate acting insulins
    • isophane susp (NPH, Humulin N)
    • isophane susp (NPH, Novolin N)
  5. Which insulin(s) have no peak time?
    • insulin detemir (Levemir)
    • insulin glargine (Lantus)
  6. Which insulin(s) must be given seperately?
    • insulin detemir (Levemir)
    • insulin glargine (Lantus)
  7. Which insulin(s) can be given IV?
    • isophane susp (NPH, Humulin N)
    • isophane susp (NPH, Novolin N)
  8. Which insulin(s) are cloudy?
    • isophane susp (NPH, Humulin N)
    • isophane susp (NPH, Novolin N)
  9. insulin aspart (NovoLog)
    • Type: Rapid Acting
    • Onset: 10-20 min
    • Peak: 1-3 hr
    • Duration: 3-5 hr
  10. In what order are insulins mixed?
    • Draw total amount of air into syringe
    • Place air into NPH (cloudy)
    • Place air into Regular
    • Draw Regular
    • Draw NPH (cloudy)
    • (Nancy Reagan, Registered Nurse)
  11. insulin lispro (Humalog)
    • Type: Rapid Acting
    • Onset: 5-15 min
    • Peak: 1–1.5 hr
    • Duration: 3-4 hr
  12. insulin glulisine (Apidra)
    • Type: Rapid Acting
    • Onset: 15-30 min
    • Peak: 1 hr
    • Duration: 3-4 hr
  13. insulin regular (Humulin R, Novolin R)
    • Type: Short Acting
    • Onset: 30-60 min
    • Peak: 1-5 hr
    • Duration: 6-10 hr
  14. isophane susp (NPH, Humulin N, Novolin N)
    • Type: Intermediate Acting
    • Onset: 1-2 hr
    • Peak: 6-14 hr
    • Duration: 16-24 hr
  15. Humulin 70/30
    • Type: Combination
    • Preparation:
    • .... 70% isophane susp
    • .... 30% insulin regular
    • Onset: 0.5
    • Peak: 6-10
    • Duration: 10-16
  16. Novolin 70/30
    • Type: Combination
    • Preparation:
    • .... 70% isophane susp
    • .... 30% insulin regular
    • Onset: 0.5
    • Peak: 6-10
    • Duration: 10-16
  17. Humulin 50/50
    • Type: combination
    • Preparation:
    • .... 50% isophane susp
    • .... 50% insulin regular
    • Onset: 0.5
    • Peak: 3-5
    • Duration:
  18. Novolog Mix 70/30
    • Type: combination
    • Preparation:
    • .... 70% insulin aspart protamine susp
    • .... 30% insulin aspart susp
    • Onset: 0.25 (15 min)
    • Peak: 1-4
    • Duration: 18-24
  19. Humalog Mix 75/25
    • Type: combination
    • Preparation:
    • .... 75% insulin lispro protamine suspension
    • .... 25% insulin lispro
    • Onset: 0.25 (15 min)
    • Peak: 1-2
    • Duration: 18-24
  20. insulin detemir (Levemir)
    • Type: Long Acting
    • Onset: 1
    • Peak: None
    • Duration: 5.7-24
  21. insulin glargine (Lantus)
    • Type: Long Acting
    • Onset: 2
    • Peak: None
    • Duration: 24
  22. List (7) oral hypoglycemics.
    • Alpha-glucosidase inhibitors
    • Biguanide
    • Meglitinides
    • Sulfonylureas, first generation
    • Sulfonylureas, second generation
    • Thiazolidinediones
    • Miscellaneous drugs
  23. List (2) alpha-glucosidase inhibitors.
    • acarbose (Precose)
    • miglitol (Glyset)
  24. List variations of biguanide.
    • metformin
    • .... immediate release (Glucophage, Riomet)
    • .... extended release (Fortamet, Glucophage XR, Glumetza)
  25. List (3) first generation sulfonylureas.
    • chlorpromamide (Diabinese)
    • tolazamide (Tolinase)
    • tolbutamide (Orinase)
  26. List (4) second generation sulfonylureas.
    • glimepiride (Amaryl)
    • glipizide (Glucotrol)
    • glyburide (DiaBeta)
    • glyburide micronized tablets (Micronase)
  27. List (2) thiazolidinediones
    • pioglitazone (Actos)
    • roziglitazone (Avandia)
  28. List (4) miscellaneous oral hypoglycemics.
    • bromocriptine (Cycloset)
    • exenatide (Byetta)
    • pramlintide (Symlyn)
    • sitagliptin (Januvia)
  29. glimepriride, (Amaryl, Apo-Glimepiride, Novo-Glimepiride)
    • Common Oral Antidiabetic Drug
    • Second-Generation Sulfonylurea
  30. glipizide, (Glucotrol)
    • Common Oral Antidiabetic Drug
    • Second-Generation Sulfonylurea
  31. glyBURIDE, (Apo-Glyburide, Diabeta, Gen-Glybe, Euglucon, Micronase)
    • Common Oral Antidiabetic Drug
    • Second-Generation Sulfonylurea
  32. glyBURIDE, micronized (Glynase Pres-Tab)
    • Common Oral Antidiabetic Drug
    • Second-Generation Sulfonylurea
  33. nateglinide, (Starlix)
    • Common Oral Antidiabetic Drug
    • Meglitinide
  34. repaglinide, (Gluco Norm, Prandin)
    • Common Oral Antidiabetic Drug
    • Meglitinide
  35. metformin, (APO-Metformin, Fortamet, Glucophage, Glumetza, Glycon, Riomet)
    • Common Oral Antidiabetic Drug
    • Biguanide
  36. acarbose, (Prandase, Precose)
    • Common Oral Antidiabetic Drug
    • Alpha – Glucosidase Inhibitor
  37. miglitol (Glyset)
    • Common Oral Antidiabetic Drug
    • Alpha – Glucosidase Inhibitor
  38. Pioglitazone, (Actos, Apo-Pioglitazone, Novo-ioglitazone)
    • Common Oral Antidiabetic Drugs
    • Thiazolidinedione
  39. Rosiglitazone (Avandia)
    • Common Oral Antidiabetic Drug
    • Thiazolidinedione
  40. Exenatide (Byetta)
    • Incretin Analog
    • Common drug that increases incretins and amylin
  41. Liraglutide (Victoza)
    • Incretin Analog
    • Common drug that increases incretins and amylin
  42. Pramlintide, (Symlin)
    • Amylin Analog
    • Common drug that increases incretins and amylin
  43. Sitagliptin (Januvia)
    • DDP-IV Inhibitor
    • Common drug that increases incretins and amylin
  44. human regular insulin (Humulin R, Novolin R)
    • Therapeutic Class: Antidiabetic agent; pancreatic hormone
    • Phamacologic Class: Short acting hypoglycemic agent
    • Action:
    • .. Promote:
    • ...... cellular uptake of glucose, amino acids, and potassium
    • ...... protein synthesis, glycogen formation and storage
    • ...... fatty acid storage as triglycerides
    • ...... utilization of glucose for energy needs
    • .. Inhibit gluconeogenesis
    • Adverse Effects: Hypoglycemia, weight gain

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