Levadopa, Carbidopa, Sinamet
- -Levadopa is a precursor to dopamine, standard tx since 1967
- -no "right" dose of Lepadova, titrated to pt's response and s/e
- -"end of dose symptoms:" pt. may freeze up or "turn off"
- -s/e: N/V, orthostatic hypotension, arrythmias, dyskinesias, vivid dreams, hallucinations
- -Carbidopa delays the conversion of levodopa to dopamine until it reaches the brain, reducing the amount of Levadopa needed.
- -Sinamet is the only combo drug avil. in the US