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How is a bruise removed?
The material is removed by phagocytes
What are the 4 activities of hemostasis following injury to the blood or blood vessels?
- 1. local spasm of arterial blood vessels and vasoconstriction (to reduce blood flow)
- 2. formation of a platelet plug to seal damaged blood vessels
- 3. activation of blood clotting factors to form stringy polymers of protein fibrin
- 4. fibrous tissue invades clot to permanently close hole
What is the advantage of hemostasis after an injury to blood/ blood vessels?
Decreases blood loss
4 steps of forming a platelet plug..
- 1. Platelets adhere to exposed collagen fivers beneath endothelium of damage vessel.
- 2. Platelets are activated and aggregate to form plug.
- 3. Platelets release their granules.
- 4. Platelet plug stops bleeding.
What reduces the chances of a blood clot forming?
Too much aspirin
Aspirin can be taken to reduce the risk of coronary thrombosis aka ___.
Heart clot/ heart attack.
What chemical releases activating Prothrombin?
Stuart Factor/ Factor X
What activates chemical reactions that result in stick Fibrin fibers?
Damaged tissue releases what?
What assists in making clotting factors needed to initiate Stuart Factor/ Factor X?
What is the group of genetic dicorders in which a "wrong" amino acid is inserted into a clotting factor protein?
What is the effect of hemophilia?
Insoluble fibrin clots do not form correctly/ the formation of the fibrin meshwork and a fibrin/ platelet clot fails.
Hemophilia A (factor 8 deficiency) is ___.
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