pharmacology exam

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cdsack
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54741
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pharmacology exam
Updated:
2010-12-10 00:17:39
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  1. inhibit bacterial cell wall synthesis
    vancomycin is the only glycopeptide antibiotic available
  2. inhibit cell wall funtion
    Polymyxin B is an example of an antibiotic that interferes with cell wall function
  3. inhibit protein synthesis - 5 classes:
    aminoglycosides
    macroslides
    tetracylines
    amphenicols
    oxazolidiones
    they reduce the number of disease causing bacteria by interfering with the ability to replicate
  4. inhibit bacterial RNA & DNA synthesis
    fluroquinolones (e.g. ciprofloxacin)
    nitroimidazoles
    (e.g. metronidazole)
  5. antifolates
    Folic acid is needed for bacterial synthesis of DNA (needs to make its own) from para-aminobenzoic acid (PABA)
    antifolate antiinfective agents (e.g. sulfonamides)
    dihydrofolate reductase inhibitors (e.g. trimethoprim)
    they block bacterial synthesis of folic acid
  6. microbial resistance is the ability of bacteria to overcome the bactericidal effects of an antibiotic
  7. Sulfonamides are anti-folate drugs
  8. trimethoprim is a dihydrofolate reductase inhibitor.
  9. Aminoglycosidesis A common ending of-” mycin “.
    Use:Serious infections of the bone, abdomen, heart, zbrain, urinary tract, reproductive system, skin, and kidneys: Examples –inflammatory disease, osteomyelitis, peritonitis, endocarditis, pelvic
    Treatment of blepharitis and conjunctivitis
    Bowel sterilization prior to bowel surger

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