Chapter 24

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Chapter 24
2010-12-11 18:38:20

Pregnancy and Breast Feeding
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  1. General Principles when prescribing drugs to pregnant patients
    • Is the drug teratogenic
    • Can the drug affect the near term fetus negatively
  2. Pregnancy Category A
    • Adequate studies have failed to demonstrate risks to the fetus; no evidence of the risk in later trimesters
    • Folic Acid
  3. Pregnancy Category B
    • Animal Studies have failed to demonstrate a risk to the fetus or no adequate studies in humans; bad effects in animals but none in humans
    • Acetaminophen, penicilins
  4. Pregnancy Category C
    • Animal studies have shown an adverse effect on the fetus and there are no adequate studies in humans; or no studies are available in either animal or women. Potential benefit may warrant use
    • Epi and Aspirin
  5. Pregnancy Category D
    • Positive evidence of human fetal risk based on adverse reaction data, but potential benefits in serious situations may warrant its use
    • Warfarin, Tetracycline
  6. Pregnancy Category X
    • Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk, never administer
    • Triazolam
  7. Pregnancy and Drugs
    • Local anesthetics have been reported to produce fetal bradycardia and neonatal depression in large doses near term
    • Lido and Prilocaine are category B
    • Bupivicaine (teratogenic in rats) Class C
    • Afternoon appt
    • Recumbent position (Not Trendelenburg)