Immunology Chap 2

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Immunology Chap 2
2010-01-30 13:28:41

Immunology Terms
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  1. Antibody
    An immunoglobulin which will bind with the antigen against which it was directed.
  2. Antigen
    Any molecule capable of producing an immune response.
  3. Antigen Presenting Cell (APC)
    Cells that process antigen and display a fragment on the cell surface in association with the MHC (major histocompatibility complex).
  4. Apoptosis
    Pre-programmed cell death or cell suicide.
  5. Cytokines
    Soluble proteins that regulate immune responses.
  6. Dendritic Cell
    One of the antigen presenting cells (APC) capable of displaying an antigen on its surface in conjunction with the MHC (major histocompatibility complex).
  7. Epitopes
    A specific region of an antigen that is recognized by B cells or T cells.
  8. Immunogen
    Any substance capable of generating an immune response.
  9. Immunoglobulin
    The more precise name for the proteins called antibodies, which migrate in the gamma globulin region in a protein electrophoresis.
  10. Interferon
    Cytokines that play a role in the immune system's response to viruses.
  11. Interleukins
    Cytokines that stimulate, promote and otherwise modulate different cells and other components of the immune system.
  12. Macrophage
    A monocyte that is one of two cells capable of phagocytosis and usually resides in tissues.
  13. Natural Killer (NK) Cells
    Cells of the innate immune system that destroy virally infected cells and some tumor cells.
  14. Negative Selection
    The process of removing T cells that overreact against host antigens, and, as a result, will undergo apoptosis in the thymus.
  15. Opsonins
    A molecule that attaches to a microbe or other antigen to facilitate its recognition by phagocytic cells.
  16. Opsonization
    The attachment process of an opsonin to an antigen.
  17. Phagocytosis
    The process by which antigens are engulfed and destroyed.
  18. Phagosomes
    Membrane-bound vacuoles which contain the phagocytized cells or particles.
  19. Positive Selection
    Elimination of T cells in the thymus which do not have the capability to recognize foreign antigens, and which undergo apoptosis as a result.
  20. T Helper Cell
    Any mature T lymphocyte that is positive for the CD4 marker (i.e., a CD4+ cell), and includes Th1 and Th2 cells.