General Anaesthetics

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Author:
rach394
ID:
57095
Filename:
General Anaesthetics
Updated:
2010-12-23 07:57:27
Tags:
pharmacology CNS
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Description:
General Anaesthetics
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  1. barbiturate anaesthetics (class) name drugs
    • thiopentone
    • methohexitone
    • pentobarbitone
  2. thiopentone
    gives rapid induction but is not good at maintaining anaesthesia
  3. propofol
    • rapid induction
    • rapid metabolism
    • non irritant
    • non cumulative
    • maintains anaesthesia
    • compatable with inhalation anaesthetics
  4. steroid anaesthetics (class) name drugs
    • alphaxolone
    • alphadolone
  5. steroid anaesthetics (class) pros
    • high TI
    • little resp depression
    • no accumulation and rapid biotransformation
  6. steroid anaesthetics (class) cons
    • excitement on recovery
    • CV depression
    • expensive
    • bad for dogs (histamine release)
  7. imidazole anaesthetics (class) name drugs
    • metomidate
    • etomidate
  8. imidazole anaesthetics (class) pros
    • no CV or resp depression
    • no cumulative effects, rapid metabolism
    • high TI
  9. imidazole anaesthetics (class) cons
    • no analgesia
    • excitement
  10. dissociative anaesthetics (class) name drugs
    • ketamine (when used as sedative, given IM)
    • tiletamine
  11. dissociative anaesthetics (class) pros
    • high TI
    • no CV or resp depression
    • non-cumulative effects
  12. dissociative anaesthetics (class) cons
    • psychic disturbances
    • involuntary movements
  13. inhalation anaesthetics (class) name drugs
    • nitrous oxide (N2O)
    • xenon
    • isoflurane
    • desflurane
    • sevoflurane
  14. inhalation anaesthetics (class) effects
    • maintain surgical anaesthesia
    • not effective analgesics
    • variable mm relaxation
    • absorbed and excreted unchanged from lungs
  15. nitrous oxide gas (N2O)
    • not sufficiently potent to be used alone (an adjunct)
    • analgesic
    • administer with minimum 33% O2

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