Immunologiska mediatorer

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Author:
Anonymous
ID:
57313
Filename:
Immunologiska mediatorer
Updated:
2010-12-28 05:28:27
Tags:
cytokiner interleukiner
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Description:
De vanligaste mediatorerna vid immunsvar, deras funktion och vilken cell som utsöndrar dem.
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  1. Histamin
    • Mastceller
    • Vasdilation
    • P-selectin
  2. PGD2, PGE2
    • Leukocyter
    • Vasodilation
    • Kärlpermeabilitet
  3. LTC4, LTD4
    • Leukocyter
    • Vasokonstriktion
    • Kärlpermeabilitet
  4. TNF-alfa, IL-1
    • Makrofager
    • ICAM
    • E-selectin
    • Kärlpermeabiliet
  5. IL-8
    • Makrofager
    • Kemotaxi
  6. LTB4
    • Leukocyter
    • Kemotaxi
  7. C5a, C4a, (C3a)
    • Komplementsystemet
    • Kemotaxi
  8. Formylerat Metionin
    • Bakterier
    • Kemotaxi
  9. IL-2
    • Aktiverade T-celler
    • Autoaktivering
  10. IL-6
    • Makrofager
    • Lever --> akutfasproteiner (CRP, kompl., MBL)
  11. IL-4
    • TH2
    • Classwitch IgE
    • B-cellsproliferation
  12. IL-5
    • TH2
    • Eosinofiler
  13. IL-10
    • TH2
    • Inhibering TH1
  14. IFN-gamma
    • TH1
    • Makrofagaktivering
  15. IL-12
    • Makrofager
    • TH1-proliferation
  16. IFN-alfa/beta
    • Virusinfekterade celler
    • Antiviralt stadium =
    • sänkt proteinsyntes,
    • ökat MCH-I-uttryck

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