Breast

Card Set Information

Author:
Anonymous
ID:
57659
Filename:
Breast
Updated:
2011-01-01 17:52:05
Tags:
Breast Absite Review
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Description:
Breast Absite Review
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  1. Receptor-positive
    • Respond better to hormones, chemo, surgery
    • Most common in post-menopausal women
    • Progesterone receptor +: better prognosis than estrogen receptor +
    • PR/ER + has the best prognosis
  2. Male Breast CA
    • Usually ductal
    • Later presentation = poorer prognosis
    • Pectoral muscle involvement
    • Risk: steroid use, XRT, Klinefelter's (high estrogen)
    • Tx:
    • Modified radical mastectomy
  3. Ductal CA
    • 85%
    • Medullary: smooth borders, increased lymphocytes, ductal type cancer with bizarre cells; favorable prognosis
    • Tubular: 10% nodes +; favorable prognosis
    • Mucinous CA (Colloid): favorable prognosis
    • Scirrhotic CA: worse prognosis
    • Tx:
    • MRM or
    • Lumpectomy with ALND or SLND
    • Postop XRT
  4. Lobular CA
    • 10%
    • No calcifications
    • Infiltrative
    • Likely BL, multifocal, multi-centric
    • +Signet ring cells: worse prognosis
    • Tx:
    • MRM or
    • Lumpectomy with ALND or SLNB
    • Postop XRT
  5. Inflammatory CA
    • Tx:
    • Chemo and XRT first
    • Mastectomy
    • Very aggressive
    • Dermal lymphatic invasion
    • Peau d'orange lymphedema

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