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Anonymous
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D2 receptor antagonist
- stimulates lactation
- domperidone
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Recombinent DNA
to treat dwarfism: inc GH
- for pit. dwarfism or GH def. short plasma t1/2 (20min)- longer biological (9-17hrs)
- base on IGF-1 levels
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somatostatin analogs
to treat inc GH
- octreotide
- lanreotide (long acting)
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Recombinent IGF-1
use to increase IGF-1
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synthetic GHRH
to increase GH
sermorelin
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GH receptor antagonist
for gigantism/ acromalegy
pegvisomat
dec IGF-1
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Dopamine agaonist
- bromocriptine (parlodel)
- cabergloine
- pergolide
- inc dopamine via D2 to dec GH
- SE: n/v postural hopotension
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