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they break down myelination ex. mercury(mad as a hatter),lead (the nero burning down rome.) and arsenic
Nodes od ranvier
the space between the mylinated cells
the PNS mylination cells
found in puffer fish it stops the function of the voltage Na sodium gates
found in south american tree frogs(when they eat food outside of S.A. they arent poisones). it keeps the voltage gated Na channels open causing it to be over whelmed and died
inhibits ACh receptors (inhibits the chemical gated Na) black widows release this.
2 different Na+ gates
- Chemical gated Na+ Nicotinic
- Chemical gated Na+ muscarinic
stops the function of ACh to be released from the cell causing paralyaze.
- the lethal dose of a given substance when 50% of the population would die from the dose.
- caffine 195mg/kg
caffine blocks the receptors so more free floating adenosine is around the cell making you feel more awake like SSRIs