imm.txt

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Author:
Anonymous
ID:
61003
Filename:
imm.txt
Updated:
2011-01-20 22:15:55
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Immunology
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  1. inborn, genetically control, non-specific biochemical and physical barriers
    INNATE
  2. Evolutionary, developed or aquired, specific,
    ADAPTIVE
  3. inflamatory response, complement system, interferons
    INNATE
  4. antigen is introduced and an antibody is formed
    ACTIVE ACQUIRED
  5. vacination and antibody is formed
    ACTIVE ACQUIRED
  6. Antibody is given to person
    PASSIVE ACQUIRED
  7. temporary in duration (natural - maternal or artificial - RhIG)
    PASSIVE ACQUIRED
  8. immediate response - IgE with mast cells
    TYPE I CELLULAR IMMUNITY
  9. skin rash, uriteria, hay fever, anaphylaxis, asthma
    TYPE I CELLULAR IMMUNITY
  10. antigen-antibody reaction with cell death through complement lysis
    TYPE II CELLULAR IMMUNITY
  11. HDN, transfusion rx, autoimmune disease, Myasthenia gravis
    TYPE II CELLULAR IMMUNITY
  12. soluble antigen-antibody form immune complexes
    TYPE III CELLULAR IMMUNITY
  13. drug related autoantibodies, serum sickness, tissue damage by anaphylatoxins, manifestations of LE
    TYPE III CELLULAR IMMUNITY
  14. chronic or delayed antigen stimulates specific T-Cell mediated cellular damage
    TYPE IV CELLULAR IMMUNITY
  15. graft vs host disease, allograft rejection, poison ivy, TB
    TYPE IV CELLULAR IMMUNITY
  16. hpersensitivity
    CELLULAR IMMUNITY
  17. circulating antibody
    HUMORAL IMMUNITY
  18. spleen, lymph nodes, thymus, liver, BM, BALT, GALT
    ORGANS OF THE IMMUNE SYSTEM
  19. phagocytosis, complement actiation (alternative pathway), epithelial barriers, inflammatory reations, toll-like receptors
    INNATE
  20. MHC
    MAJOR HISTOCOMPATIBILITY COMPLEX
  21. TNF
    TUMOR NECROSIS FACTOR
  22. MHC includes genes of ___ System and genes that encode other proteins ____ some complement components and some heat shock proteins
    MHC - TNF
  23. the genes that encode the MHC molecules are located on the short arm of chromosome ___
    6
  24. name the 3 classes of the MHC molecule
    MHC CLASS I
  25. ____ molecules are found on almost all cells of the body
    MHC CLASS I
  26. the MHC Class I molecules are defined by 3 major Class I genes
    HLA-A. -B, -C
  27. each person will express Class I HLA molecules. 2 HLA-A, 2 HLA-B, & 2 HLA-C. each loci have many alleles for each molecule
    • HLA-A = 50
    • HLA-B = 75
    • HLA-C = 30
  28. there are 3 MHC Class II gene loci
    • HLA-DP
    • HLA-DQ
    • HLA-DR
  29. there are 10 forms of Class II HLA molecules
    • HLA-DP = 2
    • HLA-DQ = 4
    • HLA-DR =4
  30. ____ molecules are heterodimeric
    Class II
  31. expressed on monocytes, macrophage, dentritic cells, and B lymphs
    Class II HLA molecules
  32. ___molecules come from proteins that have been phagoytosed and endocytosed by antigen presenting cells. they are termed exogenous antigens and include most bacteria, parasites, and viral particles released from other cells
    Class II HLA molecules
  33. ____ molecules have 20 genes coded for proteins of the complement system and proinflammatory molecules such as TNF
    MHC Class III
  34. CD markers
    Clusters of Differentiation
  35. cortcal thymocytes, some APCs and B cells, strength of expression is inverse to expression of TCR/CD3
    CD1
  36. T lymphs
    CD3
  37. pan T marker, present in early thymocytes, NK cells, sheep cell rosette receptor activation and adhesion function (LFA-2)
    CD2
  38. developing and mature thymocytes and on 2/3 perpheral T cells, T helper cells and some macrophages, adhesion molecules that mediates MHC restriction, signal transmission, HIV receptor
    CD4

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