Neuro Lecture 3
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When is the Embryonic stage and what occurs then?
- 2-8 weeks
- Organs are formed
- Limb buds form
- Cephalocaudal development
When does the Fetal Stage occur and forms then?
- 8th week until birth
- Newer systems are built upon older systems
- Nervous system continues to develop after birth
When does the Neural Plate form?
Day 18 of gestation
What does the neural plate differentiate to create?
What does the neural crest become?
What does the neural tube become?
When do the ends of the neural tube close?
- Crainial end closes on day 24 of gestation
- Caudal end closes on day 28 of gestation
Name the 3 primordial cell types
What does the endoderm become?
Digestive and respiratory components
What does the mesoderm become?
- Skeletal muscles
- Ciculatory system
- Skeletal system
- Genitourinary system
What does the ectoderm become?
- Sensory organs
- Nervous System
What are the 3 primary vesicles of the neural tube?
Name the 5 secondary vesicles of the Neural Tube
What do the 5 secondary vesicles become?
- Telencephalon - Cerebral cortex
- Diencephalon - Der
- Mesencephalon - Midbrain
- Metencephalon - Pons and cerebellum
- Myelencephalon - Medulla
When does myelination begin?
4th gestational month
What are some causes of congenital anomalies?
- Drugs or abnormal hormone levels
- Decreased oxygen
What are three ways Spinda Bifida can present?
What are three complications of a Myelomeningocele?
- Chiari malformation
- Tethered cord
What is a syrinx?
Pocket of cerebral spinal fluid trapped in the spinal cord
What are some signs of a pressence of a syrinx?
Paralysis, clonus, babinski reflex, hypertonicity (spasticity), hyperreflexive
How is hydrocephalus usally corrected?
- With a V-P shunt
What is Tetherd Cord?
- Complication of Spina Bifida
- Medical Emergency
- Solution: Cut filum terminale
What is anencephaly?
Class of failure of the neural tube to close rostrally
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