Top 100 Drugs

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pebbles135
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61162
Filename:
Top 100 Drugs
Updated:
2011-01-21 21:52:28
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  1. 1. Hydrocodone Bitartrate w/ Acetaminophen
    • Brand Name: Lortab
    • Therapeutic Class: analgesic combination (opioid)
    • MOA: hydrocodone: opioid receptor agonist, acetaminophen: analgesic MOA unknown
  2. 2. Levothyroxine Sodium
    • Brand Name: Synthroid
    • Therapeutic Class: thyroid product
  3. 3. Lisinopril
    • Brand Names: Prinivil, Zestril
    • Therapeutic Class: angiotensin-converting enzyme (ACE) inhibitor
    • MOA: ACE-I (angiotensin converting enzyme inhibitor)
  4. 4. Simvastatin
    • Brand Name: Zocor
    • Therapeutic Class: antilipemic agent
    • MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
  5. 5. Amoxicillin Trihydrate
    • Brand Name: Amoxil
    • Therapeutic Class: antibiotic
    • MOA: inhibits cell wall synthesis of mucopeptide
  6. 6. Azithromycin Dihydrate
    • Brand Names: Zithromax, Zmax
    • Therapeutic Class: antibiotic
    • MOA: inhibits microbial protein synthesis
  7. 7.Atorvastatin Calcium
    • Brand Name: Lipitor
    • Therapeutic Class: antilipemic agent
    • MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors´╗┐
  8. 8. Metformin Hydrochloride
    • Brand Name: Glucophage
    • Therapeutic Class: antidiabetic agent
    • MOA: main effect believed to inhibition of hepatic gluconeogenesis
  9. 9. Hydrochlorothiazide
    • Hydrochlorothiazide (Microzide)
    • Therapeutic Class: diuretic
    • MOA: diuretic effect: blocks re-absorption of sodium and chloride from renal tubules, antihypertensive effect: unknown
  10. 10. Alprazolam
    • Brand Name: Xanax
    • Therapeutic Class: benzodiazepine
    • MOA: binds to receptors in the central nervous system (CNS)
  11. 11. Albuterol Sulfate (salbutamol)
    • Brand Name: Proventil HFA®, Proair HFA®, Ventolin HFA ®
    • Therapeutic Class: beta2 agonist
    • MOA: beta-2 receptor agonist
  12. 12. Metoprolol Succinate
    • Brand Name: Toprol-XL
    • Therapeutic Class: 24:24 beta adrenergic blocking agent
    • MOA: beta-1 receptor blocker
  13. 13. Atenolol
    • Brand Name: Tenormin
    • Therapeutic Class: antianginal
    • MOA: beta-1 receptor blocker
  14. 14. Furosemide
    • Brand Name: Lasix
    • Therapeutic Class: diuretic (loop)
    • MOA: "loop diuretic": blocks sodium and chloride re-absorption from kidney tubules
  15. 15. Amlodipine Besylate
    • Brand Name: Norvasc
    • Therapeutic Class: calcium channel blocker
    • MOA: dihydropyridine calcium channel blocker
  16. 16. Zolpidem Tartrate
    • Brand Name: Ambien® & Ambien CR®
    • Therapeutic Class: hypnotic
    • MOA: agonist of benzodiazepine GABA-A subunit
  17. 17. Potassium Chloride
    • Potassium Chloride (K Dur)
    • Therapeutic Class: electrolyte supplement
    • MOA: potassium supplement
  18. 18. Metoprolol Tartrate
    • Brand Name: Lopressor
    • Therapeutic Class: beta blocker
    • MOA: beta-1 receptor blocker
  19. 19. Oxycodone Hydrochloride with Acetaminophen
    • Brand Name: Percocet
    • Therapeutic Class: analgesic (opioid)
    • MOA: oxycodone: opioid receptor agonist, acetaminophen: analgesic MOA unknown
  20. 20. Sertraline Hydrochloride
    • Brand Name: Zoloft
    • Therapeutic Class: antidepressant
    • MOA: SSRI (selective serotonin reuptake inhibitor)
  21. 21. Omeprazole
    • Brand Name: Prilosec
    • Therapeutic Class: proton pump inhibitor
    • MOA: PPI
  22. 22. Esomeprazole Magnesium
    • Brand Name: Nexium
    • Therapeutic Class: proton pump inhibitor
    • MOA: PPI
  23. 23. Prednisone
    • Brand Name: Prednisone
    • Therapeutic Class: corticosteroid
    • MOA: inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
  24. 24. Escitalopram Oxalate
    • Brand Name: Lexapro
    • Therapeutic Class: antidepressant
    • MOA: SSRI
  25. 25. Warfarin Sodium (Crystalline)
    • Brand Name: Coumadin
    • Therapeutic Class: anticoagulant
    • MOA: vitamin K epoxide reductase inhibitor (inhibitor factos II, VII, IX, and X)
  26. 26. Montelukast Sodium
    • Brand Name: Singulair
    • Therapeutic Class: leukotiene receptor antagonist
    • MOA: leukotriene receptor antagonist
  27. 27. Ciprofloxacin Hydrochloride
    • Brand Name: Cipro (XR)
    • Therapeutic Class: antibiotic
    • MOA: inhibits bacterial DNA synthesis
  28. 28. Ibuprofen
    • Brand Name: Motrin
    • Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
    • MOA: exhibits analgesic and antipyretic activities by inhibiting prostaglandin synthesis.
  29. 29. Clopidogrel Bisulfate
    • Brand Name: Plavix
    • Therapeutic Class: antiplatelet agent
    • MOA: platelet adenosine diphosphate (ADP) receptor antagonist
  30. 30. Fluoxetine Hydrochloride
    • Brand Name: Prozac
    • Therapeutic Class: antidepressant
    • MOA: SSRI (Serotonin Reuptake Inhibitor)
  31. 31. Tramadol Hydrochloride
    • Brand Name: Ultram
    • Therapeutic Class: analgesic (opioid)
    • MOA: binds to opioid receptor and also inhibits reuptake of norepinephrine (NE) and 5-HT
  32. 32. Cephalexin
    • Brand Name: Keflex
    • Therapeutic Class: Antibiotic
    • MOA: inhibition of bacterial cell-wall synthesis.
  33. 33. Lorazepam
    • Brand Name: Ativan
    • Therapeutic Class: benzodiazepine
    • MOA: binds to receptors in the central nervous system (CNS)
  34. 34. Clonazepam
    • Brand Name: Klonopin
    • Therapeutic Class: benzodiazepine
    • MOA: believed to enhance GABA activity
  35. 35. Citalopram Hydrobromide
    • Brand Name: Celexa
    • Therapeutic Class: antidepressant
    • MOA: SSRI
  36. 36. Bupropion Hydrochloride
    • Brand Name: Wellbutrin (SR, XL)
    • Therapeutic Class: antidepressant
    • MOA: inhibits dopamine (DA) and norepinephrine (NE) uptake
  37. 37. Gabapentin
    • Brand Name: Neurontin
    • Therapeutic Class: anticonvulsant
    • MOA: unknown
  38. 38. Propoxyphene Napsylate with Acetaminophen
    • Brand name: Darvocet
    • Therapeutic Class: analgesic combination (opioid)
    • MOA: acetaminophen: analgesic effect unknown, propoxyphene: binds to opioid receptor (like codeine, hydrocodone)
  39. 39. Lisinopril with Hydrochlorothiazide
    • Brand: Zestoretic®, Prinzide®
    • Therapeutic Class: angiotensin converting enzyme (ACE) inhibitor
    • MOA: ACE-I
  40. 40. Triamterene with Hydrochlorothiazide
    • Brand Name: Dyazide
    • Therapeutic Class: diuretic (potassium sparring)
    • MOA: triamterene: inhibits the re-absorption of sodium in exchange for potassium and hydrogen ions in the renal tubule, HCTZ: inhibits sodium and chlorine re-asborption at the distal renal tubule
  41. 41. Amoxicillin Trihydrate with Clavulanate Potassium
    • Brand Name: Augmentin® (XR)
    • Thherapeutic Class: Antibiotic
    • MOA: the acid protect amoxicillin against beta lactamases, amoxicillin inhibits the biosynthesis of cell wall mucopeptide.
  42. 42. Cyclobenzaprine Hydrochloride
    • Brand Name: Flexeril
    • Therapeutic Class: skeletal muscle relaxant
    • MOA: reduces motor activity in brain stem
  43. 43. Sulfamethoxazole with Trimethoprim
    • Brand Name: Bactrim
    • Therapeutic class: antibiotic
    • MOA: sulfamethazole: inhibits production of dihydrofolic acid, which kills bacteria, trimethoprim: interferes with the production of folic acid. Again, bacteriocida
  44. 44. Venlafaxine Hydrochloride
    • Brand Name: Effexor (XR)
    • Therapeutic Class: antidepressant
    • MOA: potentiate activity of serotonin, norepinephrine, and dopamine
  45. 45. Lansoprazole
    • Brand Name: Prevacid
    • Therapeutic Class: proton pump inhibitor
    • MOA: PPI
  46. 46. Fluticasone Propionate with Salmeterol Xinafoate
    • Brand Name: Advair
    • Therapeutic Class: beta2 agnoist
    • MOA: fluticasone: inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation), salmeterol: beta-2 receptor agonist
  47. 47. Trazodone Hydrochloride
    • Brand Name: Desyrel
    • Therapeutic Class: antidepressant
    • MOA: unknown, believed to increase serotonin levels
  48. 48. Paroxetine Hydrochloride
    • Brand Name: Paxil (CR)
    • Therapeutic Class: Psycotropic
    • MOA: Selectively inhibits the reuptake of serotonin into neurons
  49. 49. Fexofenadine HCl
    • Brand name: Allegra
    • Therapeutic Class: histimine H1 antagonist
    • MOA: inhibits the release of histamine from mast cells and selectively antagonizes peripheral histamine (1)- receptor activity.
  50. 50. Fluticasone Propionate (nasal)
    • Brand Name: Flonase™
    • Therapeutic Class: corticosteroid
    • MOA: glucocorticoid receptor agonist
  51. 51. Alendronate Sodium
    • Brand name: Fosamax
    • Therapeutic Class: biphosphonate derivative
    • MOA: osteoclast inhibitor
  52. 52. Valsartan
    • Brand Name: Diovan
    • Therapeutic Class: angiotensin II receptor blocker
    • MOA: angiotensin receptor blocker (ARB)
  53. 53. Glipizide
    • Brand name: Glucotro
    • lTherapeutic Class: antidiabetic agent
    • MOA: sulfonylurea, increase pancreatic insulin secretion
  54. 54. Lovastatin
    • Brand Name: Mevacor
    • Therapeutic Class: antilipemic agent
    • MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
  55. 55. Rosuvastatin Calcium
    • Brand name: Crestor
    • Therapeutic Class: antilipemic agent
    • MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
  56. 56. Carvedilol
    • Brand Name: Coreg, Coreg CR
    • Therapeutic Class: beta blocker with alpha-blocking activity
    • MOA: non-selective beta receptor blocker
  57. 57. Amphetamine and Dextroamphetamine Salts
    • Brand Name: Adderall
    • Therapeutic Class: stimulant
    • MOA: sympathetic amine with effects similar to epinephrine
  58. 58. Ezetimibe with Simvastatin
    • Brand Name: Vytorin
    • Therapeutic Class:
    • MOA: ezetimibe is a selective intestinal cholesterol inhibitor and prevents the abosorption of phytosterol.simvastatin is a HMG-CoA reductase inhibitor.
  59. 59. Duloxetine Hydrochloride
    • Brand Name: Cymbalta
    • Therapeutic Class: antidepressant
    • MOA: SSNRI (selective serotonin and norepinephrine reuptake inhibitor)
  60. 60. Diazepam
    • Brand name: Valium
    • Therapeutic Class: benzodiazepine
    • MOA: binds to receptors in the central nervous system (CNS)
  61. 61. Pravastatin Sodium
    • Brand Name: Pravachol
    • Therapeutic Class: antilipemic agent
    • MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
  62. 62. Acetaminophen with Codeine Phosphate
    • Acetaminophen with Codeine
    • Therapeutic Class:
    • MOA:
  63. 63. Amitriptyline Hydrochloride
    • Brand Name: Elavil
    • Therapeutic Class: antidepressant
    • MOA: increases 5HT and NE levels (prevents reuptake)
  64. 64. Valsartan with Hydrochlorothiazide
    • Brand Name: Diovan-HCT
    • Therapeutic Class: angiotensin II receptor blocker
    • MOA: angiotensin receptor blocker (ARB)
  65. 65. Naproxen
    • Brand Name: Naprosyn
    • Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
    • MOA: unknown but maybe related to inhibition of prostaglandin synthetase
  66. 66. Fluconazole
    • Brand Name: Diflucan
    • Therapeutic Class: antifungal
    • MOA: triazole antifungal agent that inhibits fungal sterol synthesis leading to aggregation of 14 alpha-methyl sterols in fungi, which is responsible for the fungistatic activity.
  67. 67. Levofloxacin
    • Brand Name: Levaquin
    • Therapeutic Class: antibiotic
    • MOA: inhibits DNA gyrase, enzyme required for DNA replication, transcription, repair, and recombination.
  68. 68. Enalapril Maleate
    • Brand Name:Vasotec
    • Therapeutic Class: hypertension
    • MOA: ACE-inhibitor
  69. 69. Ranitidine Hydrochloride
    • Brand Name: Zantac
    • Therapeutic Class: histamine H2 antagonist
    • MOA: histamine-2 (H2) antagonist
  70. 70. Doxycycline Hyclate
    • Brand Name: Vibramycin
    • Therapeutic Class: antibiotic
    • MOA: inhibits bacterial protein synthesis
  71. 71. Pioglitazone Hydrochloride
    • Brand name: Actos
    • Therapeutic Class: antidiabetic agent
    • MOA: peroxisome proliferator-activated receptor (PPAR) gamma agonist
  72. 72. Pantoprazole Sodium
    • Brand name: Protonix
    • Therapeutic Class: proton pump inhibitor
    • MOA: PPI
  73. 73. Carisoprodol
    • Brand Name: Soma
    • Therapeutic Class: skeletal muscle relaxant
    • MOA: unknown, works centrally to produce muscle relaxation
  74. 74. Digoxin
    • Brand Name: Lanoxin
    • Therapeutic Class:
    • MOA: Inhibits sodium-potassium ATPase, which increases intrcellular sodium concentration leading to increased intrcellular calcium concentration.
  75. 75. Allopurinol
    • Brand Name: Zyloprim
    • Therapeutic Class: xanthine oxidase inhibitor
    • MOA: decreases uric acid production
  76. 76. Methylprednisolone
    • Brand Name: Medrol
    • Therapeutic Class: synthetic glucocorticoid
    • MOA: anti-inflammatory
  77. 77. Meloxicam
    • Brand Name: Mobic
    • Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
    • MOA: May be related to prostaglandin synthetase inhibition.
  78. 78. Insulin Glargine (rDNA origin)
    • Brand Name: Lantus
    • Therapeutic class: insulin (long-acting)
    • MOA: synthetic insulin
  79. 79. Amlodipine Besylate with Benazepril Hydrochloride
    • Brand Name: Lotrel
    • Therapeutic Class: Hypertension
    • MOA: Amlodipine is a calcium channel blocker. Benazepril is a ACE inhibitor and a prodrug for benazeprilat
  80. 80. Tamsulosin Hydrochloride
    • Brand name: Flomax
    • Therapeutic Class: alpha blocker
    • MOA: alpha-1 receptor antagonist
  81. 81. Quetiapine Fumerate
    • Brand Name: Seroquel
    • Therapeutic Class: antipsychotic agent
    • MOA: serotonin (5HT), dopamie (DA), histamine and alpha receptor blockers
  82. 82. Clonidine Hydrochloride
    • Brand Name: Catapres
    • Therapeutic Class: alpha2-adrenergic agonist
    • MOA: alpha-2 receptor agonist
  83. 83. Ezetimibe
    • Brand Name: Zetia
    • Therapeutic Class: antilipemic agent
    • MOA: cholesterol absorption inhibitor (CAI)
  84. 84. Diltiazem Hydrochloride
    • Brand Name: Cardizem (CD)
    • Therapeutic Class: antiarrhythmic agent
    • MOA: non-DHP CCB
  85. 85. Fenofibrate
    • Brand Name: TriCor
    • Therapeutic Class: antilipemic agent
    • MOA: peroxisome proliferator-activated receptor (PPAR) alpha agonist
  86. 86. Celecoxib
    • Brand Name: Celebrex
    • Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
    • MOA: cyclo-oxygenase 2 inhbitor
  87. 87. Norgestimate with Ethinyl Estradiol
    • Brand Name: Ortho Tri-Cyclen
    • Therapeutic Class: Birth control
    • MOA: suppresses gonadotropins, inhibition of ovulation
  88. 88. Mometasone Furoate Monohydrate (intranasal)
    • Brand Name: Nasonex
    • Therapeutic Class: corticosteroid
    • MOA: anti inflammatory, antipruritic, and vasoconstrictive
  89. 89. Estrogens (Conjugated)
    • Brand Name: Premarin
    • Therapeutic Class: estrogen derivative
    • MOA; estrogen receptor agonist
  90. 90. Promethazine HCl
    • Brand Name: Phenergan
    • Therapeutic Class: antiemetic
    • MOA: H-1 receptor blocker
  91. 91. Sildenafil Citrate
    • Brand Name: Viagra
    • Therapeutic Class: ED and Pulmonary hypertension
    • MOA: inhibits cGMP specific phosphodiesterase type-5 in smooth muscle, where PDE5 is responsible for degradation of cGMP. And can inhance the effect of NO.
  92. 92. Drospirenone with Ethinyl Estradiol (24)
    • Brand Name: Yaz
    • Therapeutic Class: Birth control CCC
    • MOA: suppresses ovulation, and causes cervical muscus changes that block sperm penetration.
  93. 93. Pregabalin
    • Brand name: Lyrica
    • Therapeutic Class: analgesic
    • MOA: unknown, may bind to alpha(2)-delta receptors in the CNS
  94. 94. Ramipril
    • Brand Name: Altace
    • Therapeutic Class: Hypertension
    • MOA: ACE-inhibitor
  95. 95. Isosorbide Mononitrate
    • Brand Name: Imdur
    • Therapeutic Class: vasodilator
    • MOA: organic nitrate, which causes arterial and venous dilation
  96. 96. Folic Acid
    • Folic Acid
    • Therapeutic Class:
    • MOA: after conversion to tetrahydrofolic acid, is necessary for normal erythropoiesis, metabolism of a.a., and metabolism of histidine.
  97. 97. Spironolactone
    • Brand name: Aldactone
    • Therapeutic class: diuretic (potassium-sparing)
    • MOA: aldosterone antagonist at the distal convoluted renal tubule
  98. 98. Glimepiride
    • Brand Name: Amaryl
    • Therapeutic Class: antidiabetic agent
    • MOA: releases insulin from functino pancreatic beta cells and produces increase in sensitive of peripheral tissues to insulin via an extrapancreatic mechainsm .
  99. 99. Valacyclovir
    • Brand Name: Valtrex
    • Therapeutic Class: L-valyl ester prodrug of acyclovir
    • MOA: inhibits replicaqtion of herpes vial DNA by competitve inhibition of viral DNA polymerase, incorporation and termination of the growinf viral DNA chain, and by inactivation of viral DNA polymerase.
  100. 100. Losartan Potassium
    • Brand Name: Cozaar
    • Therapeutic Class:
    • MOA: a reverible, non competitive, angiotensin II receptor antagonist. it deters vasoconstriction and aldosterone-secreting effects by intercepting the binding of angiotensin II to the AT (1) receptor.

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