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What are the subunits of prokaryotic RNA pol?
2 alpha, one beta and one beta prime
What factor is needed for initiation of transcription in prokaryotes?
When does sigma factor dissociated from the Pol?
What drug binds to the beta subunit of polymerase preventing transcription?
What drug intercalates between DNA preventing transcription?
What happens in lupus?
pt makes ab against snRNP
Beta thalasemia results from what?
faulty splicing, single nucleotide mutation
During what prokaryotic termination does a palindromic sequence form a loop which destabilizes the RNA pol?
What happens during rho dependent termination?
rho recognizes the sequence and helicase disrupts the stability