DNA Transcription

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Author:
pszurnicki
ID:
61547
Filename:
DNA Transcription
Updated:
2011-01-23 21:40:44
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DNA Transcription
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Description:
DNA Transcription
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  1. What are the subunits of prokaryotic RNA pol?
    2 alpha, one beta and one beta prime
  2. What factor is needed for initiation of transcription in prokaryotes?
    sigma
  3. When does sigma factor dissociated from the Pol?
    during elongation
  4. What drug binds to the beta subunit of polymerase preventing transcription?
    Rifampin
  5. What drug intercalates between DNA preventing transcription?
    actinomyocin D
  6. What happens in lupus?
    pt makes ab against snRNP
  7. Beta thalasemia results from what?
    faulty splicing, single nucleotide mutation
  8. During what prokaryotic termination does a palindromic sequence form a loop which destabilizes the RNA pol?
    rho independent
  9. What happens during rho dependent termination?
    rho recognizes the sequence and helicase disrupts the stability

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