Micro 5

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Author:
Anonymous
ID:
62190
Filename:
Micro 5
Updated:
2011-01-26 14:46:01
Tags:
GI bacteria
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Description:
GI bacteria
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  1. C. difficile
    • Ana, +, spore, rod,
    • pseudomembranous colitis
    • fecal-oral
    • A-B
    • oral metronidazole
  2. C. botulinum
    • Ana, +, spore, rod,
    • descending paralysis, double vision,
    • A,B,C1…toxins, blocks Ach release,
    • horse antitoxin
  3. C perfringens
    • Ana, +, spore, rod,
    • gas gangrene,
    • superantigen,
    • resolves in 24 hours
  4. L. monocytogenes
    • Fac Ana, +, motile, rod, 4C, Gastroenteritis, Meningitis =
    • fever, headache, stiff neck, vomit,
    • cheese,
    • phagocytes, actin rocket, Lysteriolysin,
    • ampicilin and gentimycin
  5. S. dysenteriae
    • Fac Ana, Non-lac, non-motile, -, rod,
    • most pathogenic enteric, ileum/colon (not blood),
    • A-B (ribosome), fecal-oral, ciprofloxacin,
    • 1-4 day inc, fever, cramp, bloody stool, sloughed MALT epithelium
  6. Salmonella
    • Fac Ana, Non-lac, motile, -, rod, H2S, O/H/Vi(capsular),
    • Stool sample for EC, Blood for SC Ceftriaxone, Ciprofloxacin,
    • (Ampicillin if carrier),
    • Vaccine for high risk areas
  7. Enterocolitis
    • Type III secretion,
    • grow in phagosome,
    • 12-24 hr incubation,
    • (Carrier state w/ antibiotics)
  8. Septicemia
    • Sickle cell/cancer,
    • osteomyelitis,
    • metastatic abscess
  9. Typhoid
    • GI, Peyers patch(phagocyte), Liver/spleen/GB,
    • flu/constipation for week,
    • bacteremia = fever, dilirium, “rose spots”, enlarged spleen
  10. E. coli
    • Ana, Lac, -, rod,
    • O/H/K antigens,
    • infants = gentimycin or polymixin
  11. ETEC
    Travellers diarrhea, SI, adhesin, Cholera like toxin, Pepto/fluoroquinolone
  12. EIEC
    LI,like shigella but epithelium only
  13. EPEC
    plasmid, microvilli loss, actin pedestal
  14. EHEC
    • SLT, hemolytic uremic system, LI,
    • hamburgers,
    • specialized antibiotics to avoid SLT
  15. V. Cholera
    • Curved, -, rod, tolerate acid and salt,
    • SI, pili, no damage,
    • A-B toxin, Adenylate cyclase, heat liable, ends with normal shedding
  16. C. Jejuni
    • Curved, motile, microaero, -, rod,
    • most common cause of Diarrhea,
    • Guillian-Barre (after 10 days),
    • SI/LI epithelium,
    • raw poultry,
    • Erythromycin or Ciprofloxacin (if severe)
  17. H. pylori
    • Short, Spiral, microaero, -, rod,
    • sheathed flagella, urease,
    • CagA = malignant, VacA = urea,
    • Stomach cancer,
    • urea breath test,
    • 2 antimicrobials + stomach acid inhibitor

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