ID Exam 1-Falcione

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mtr14
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62260
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ID Exam 1-Falcione
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2011-01-26 20:38:48
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  1. Clinical Presentation of Typhoid Fever
    little or no diarrhea
  2. Treatment
    of typhoid fever
    • there is resistance to flouroquinolones, so we need to test the isolate for susceptibility …
    • sometimes there may be a false susceptible result so we have the lab test again
    • to ensure it really is susceptible
  3. Treatment
    of Non-typhoidal Salmonella gastroenteritis
    • No vaccine is
    • available … however, vaccine for typhoidal Salmonella is available
  4. Treatment
    of Klebsiella pneumonia/oxytoca
    • carbapenemase-producing species are increasing …
    • normally B-lactam class treat this species, but Klebsiella produces
    • B-lactamases of an extended spectrum that are resistant to all B-lactams
    • (including carbapenams)
  5. Treatment
    of Vibrio cholera
    • 1st line
    • agents: doxycycline, tetracycline, or cipro (adults) TMP/SMX (children)
  6. Which of the
    following is NOT a member of the Enterobacteriaceae family.

    a. E.coli

    b. Proteus

    c. Enterobacter

    d. Enterococcus
    D
  7. Which of the
    following best describes the morphology (shape) of Vibrio cholera on Gram’s stain?

    a. Gram-negative diplococci

    b. Gram-positive rods, box-car

    c. Gram-negative rod, comma shaped

    d. Gram-positive cocci, lancet
    shaped
    C
  8. All salmonella
    species are non-motile microorganisms, they do not possess flagella.

    a. True

    c. False
    C
  9. Which of the
    following Salmonella species is responsible for Typhoid fever?

    a. Salmonella Paratyphi

    b. Salmonella Typhinurium

    c. Salmonella Typhi
    C
  10. Which of the
    following only colonize humans?

    a. Salmonella Typhinurium

    c. Salmonella Typhi
    C
  11. The pathogenesis of
    which of the following bacteria does NOT involve invasion of intestinal cells?

    a. EAEC

    b.
    EHEC

    c.
    EIEC
    A
  12. Which of the
    following may have been the reservoir from which Heather acquired the Salmonella Enterididis infection

    a. Her pet turtle

    b. Eggs that were transovarially
    infected

    c. Undercooked hamburger that was
    contaminated with fecal material

    d. All of the above
    D
  13. Heather’s mother
    requests antibiotics for Heather from the pediatrician since they are free at
    the local grocery store pharmacy.

    a. Salmonella Enterididis is
    a self-limiting infection, since Heather’s diarrhea is

    resolving she should not
    receive antibiotics

    b. Salmonella Enterididis always requires treatment with antibiotics and Heather

    should have been started on
    these when she was diagnosed

    c. Salmonella Enterididis always requires treatment with antibiotics and
    Heather

    should have been started on
    ciprofloxacin when she was diagnosed
    A
  14. Which of the
    following is the most common cause of Traveler’s diarrhea

    a. ETEC, which occurs with an abrupt onset and resolves in 24-48 hours

    b. ETEC, which occurs with an abrupt onset and resolves in 3-5 days

    c. ETEC, which occurs with a slow onset and resolves in 7-10 days
    A
  15. The drug of choice
    for the treatment of Typhoid fever is norfloxacin.

    a. True

    c. False
    C
  16. A licensed vaccine in
    the United States currently exists to prevent which of the following?

    a. Typhoid

    b. Shigellosis

    c. Cholera

    d. All of the above
    A
  17. Children between the
    ages of 6 months-5 years old have the highest incidence of

    Shigellosis

    a. True

    c. False
    A
  18. Which of the
    following bacteria produce exotoxin?

    a. Shigella

    b. E. Coli

    c. Cholera

    d. All of the above
    D
  19. Which of the
    following best describes the pathogen E.coli
    O157:H7

    a. A serotype of EIEC which is most common in the Southern United
    States

    b. A serotype of EIEC which is most
    common in the Southern Hemisphere

    c. A serotype of EHEC which is most common in the Southern United
    States

    d. A serotype of EHEC which is most
    common in the Southern Hemisphere

    e. A serotype of EHEC which is more common in the United States than in
    the

    Southern Hemisphere
    E
  20. Which of the
    following are capable of producing dysenteric diarrhea?

    a. Shigella

    b. Enteropathogenic E. Coli

    c.
    Enteroinvasive
    E. Coli

    d. a and c only

    e. All of the above
    D
  21. Which of the
    following is FALSE regarding Enterohemorrhagic E. Coli.?

    a. Outbreaks have been associated
    with undercooked meat

    b. Hemolytic uremic syndrome may
    develop as a complication

    c. A common serotype in the United
    States is O157:H7

    d. Antibiotic therapy may result in
    bacterial cell lysis and increased toxin release

    e. All of the above are true
    E
  22. Which of the
    following is FALSE about Vibrio cholerae?

    a. It causes a watery (rice-water)
    diarrhea

    b. It causes a painful and
    foul-smelling diarrhea

    c. It can be fatal within 24 hours

    d. First-line therapy is a single
    dose of doxycycline
    B
  23. Which of the
    following presenting signs or symptoms warrants an investigation to determine
    if a patient complaining of diarrhea is infected with E. Coli 0157:H7

    a. Headache

    b. Blood in the stool

    c. Thirst
    B
  24. Which of the
    following is TRUE regarding infectious
    diarrhea due to Shigella

    a. Shigella sonnei accounts for the majority of cases in the United
    States

    b. It is generally a self-limiting
    disease

    c. Antibiotics shorten the period of
    fecal shedding

    d. All of the above

    e. None of the above
    D
  25. Passage across
    M-cells, incorporation into and eventual expulsion out of macrophages, the use
    of invasins to enter epithelial cells from underneath, and the use of actin filaments that producing comet-like
    tails and propel the pathogen from cell to cell describes the pathogenesis of
    which agent of infectious diarrhea?

    a.
    Salmonella

    b. Shigella

    c. E. coli

    d. Vibrio cholerae

    e. Clostridium difficile
    B
  26. Which of the
    following is TRUE about
    Uropathogenic/Extraintestinal E. coli

    a. Virulence factors include
    endotoxin and hemolysins

    b. They are normal inhabitants
    (normal flora) of the human colon

    c. They can be transmitted
    vertically and horizontally

    d. They are common causes of urinary
    tract infections and bacteremia

    e. Antibiotic resistance mechanism
    include the production of beta-lactamases

    f. None of the above

    g. All of the above
    G

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