Bact: Pathogenesis Factors
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3 Primary Bacterial Pathogenesis Factos:
- Host Susceptibility
- Bacterial Infectivity
- Virulence Factors
What alters host susceptibility?
What alters bacterial infectivity?
What alters virulence factors?
- Non-fimbrial adhesions
Mannheimia haemolytica affects ____, but not ____
cattle, not dogs
E. coli affects ____, but not ___
neonatal calves, but not adult cattle
Specific strains of E. coli produce ___, causing _____ dz
____ has a capsule to avoid phagocytosis
Pathogenic E. coli have pili to...
attach to mucosa and produce enterotoxin
organism that causes dz
establishment of pathogen in host
ex. obligate pathogen:
ex. Primary Pathogen and it's secondary pathogen
- Chlamydophila felis (conjunctiva in cats)
ex. Opportunistic Pathogen (2)
- E. coli -> UTI or otitis externa
- Staphylococcus w/ chlamydophilia felis in cats (also secondary pathogen)
ex. of exogenous pathogen
Bacillus anthracis (soil-> animal)
ex. of endogenous pathogen
Gingivitis in dogs from commensal
ex. of contagious dz's (2)
- strangles in horses (streptococcus equi)
- Pneumonic Plague in cats and humans (yersinia pestis)
Bordetella bronchiseptica enters via..
inhalation (dog -> cat -> pneumonia)
Salmonella enters via...
ingestion (feed -> cattle)
Lepto enters via...
Skin Abrasion, mucosa (water-> GI)
Brucellosis canis enters via...
Brucellosis enters via...
Placenta to fetus
E. Coli in claves enters via...
spread by contact, food, water
Transmission from mother to offsrping during pregnancy
streptococcus equi is ___ specific
Brucella abortus is ___ specific
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