Lecture 9: Blood

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  1. Anisocytosis
    abnormal RBC size
  2. microcyte
    macrocyte
    • <6um
    • >9um
  3. Hereditary spherocytosis
    defects in ankyrin, spectrin, or band 3.
  4. Hereditary elliptocytosis
    defects in spectrin or band 4.1
  5. neutrophil
    • PMN
    • Primary, non-specific granules- azurophilic lysosome
    • Secondary, specific granules- antimicrobial function
    • Tertiary granules- phosphatases & metalloproteinases such as gelatinases/collagenases
    • Band cells
    • Integrin
  6. Eosinophil
    • stain red
    • LARGER parasites- degranulate surpface of parasite
    • major basic protein
  7. basophils
    • allergic
    • release histamine-bronchial constriction & SMC vasodialation, serotonin

    *anaphylatic shock- hypotension
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Lecture 9: Blood
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blood
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