Physiology Adrenal Glands
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What is the pathway synthesis for norepinephrine and epinephrine?
Pheochromocytoma is caused by what?
adrenal medulla tumor
What are the symptoms of pheochromocytoma?
- Elevated blood pressure
The tumore in Pheochromocytoma is derived from what cells?
Concentration of what ion can directly influence the secretion of Aldosterone?
Sexual infatilism results from which congenital adrenal hyperplasia?
17 alpha hydroxylase deficiency
What is the number one cause of Cushing's Syndrome?
What are endogenous causes for Cushing's syndrome?
- Ant. Pituitary adenoma--high ACTH
- Ectopic ACTH from a small cell lung cancer..high ACTH
- Adrenal adenoma----low ACTH
Cushing's syndrome is caused by?
High cortisol levels
What are the symptoms of Cushing's syndrome?
Moon face, Buffalo hump, truncal obesity, hypertension
Dexamethasone suppresion test is done for what purpose?
To determine whether Cushings syndrome is caused by a Pituitary adenoma
Low level of dexamethasone would yield what results in a person with high levels of cortisol?
High level of cortisol would remain constant
High level of dexamethasone administration would result in what cortisol levels in a person with high cortisol level?
Cortisol levels would remain high in ectopic ACTH or Adrenal adenoma ACTH but would be lower if an Ant. Pituitary adenoma was producing ACTH
High levels of ACTH result in what skin condition?
What is the differentiating feature of neuroblastoma and Pheochromocytoma?
In Pheochromocytoma you get episodic hypertension
What is Conn's Syndrome?
Alkalosis is usually results in what?
What is the difference between primary (Conn's Syndrome) and a secondary Hyperaldosteronism?
- Conn's syndrome--low renin bc volume increases
- secondary hyperaldosteronism--high renin bc volume doesn't increase
What are the effects of aldosterone?
- Na+ absorption/K+excretion
- H+ excretion
- H20 absorption
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