(Rh (D) Immune Globulin)
Immunoglobulin ( A blood product)
Causes destruction of any fetal RH pos RBCs that might have entered maternal circulation before the Rh negative mother has time to build up antibodies that will destroy the rbcs of future RH + fetuses.
Given IM within 72 hours to RH negative mother after termination of pregnancy with RH positive baby. (delivery or abortion). Also given prophylactically at 28 weeks gestation ( minidose)
Contraindications: Hypersensitivity, previously sensitized mothers,
Side Effects: Lethargy, myalgia, local stiffness, tenderness at site, Anaphylaxis.
Type and cross match neonatal cord blood b/c mother must be Rh negative and not previously sensitized.
Baby must be Rh positive with negative direct Coombs
2 RNs must check lot number, sign document together. Blood consent may have to be signed.
Must be administered with 72 hours after termination of pregnancy.