Defects in one or more of these mitochondrial proteins reduce the amount of __ teh cell can make and have been shown to cause rare human disorders. Because the parts of the body most susceptible to energy deprivation are the nervous system and the muscles, most __ diseases primarily affect these systems.
-- For ex., __ causes weakness, intolerance of exercise, and muscle deterioration. Another mitochondrial disorder is __, which can produce sudden blindness in people as young as 20 and 30. The four mutations found thus far to cause this disorder affect __ during cellular respiration, a crucial function for teh cell.
- mitochondrial myopathy
- Leber's hereditary optic neuropathy
- oxidative phosphorylation