Immunology T1Ch2

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Author:
Anonymous
ID:
64539
Filename:
Immunology T1Ch2
Updated:
2011-02-06 20:09:49
Tags:
immunology
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Description:
test 1 chapter 2
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  1. Organs are grouped into 2 main groups:
    Primary and secondary lymphoid organs
  2. primary lymphoid organs include:
    bone marrow and thymus
  3. secondary lymphoid organs include:
    spleen and lymph nodes
  4. There are tertiary lymphoid organs:
    GALT, BALT, genitourinary system

    **only have effector and memory cells**
  5. hematopoiesis
    formation and development of red and white blood cells
  6. all blood cells arise form
    hematopoietic stem cells (HSC)
  7. Why are HSCs difficult to study? (2 reasons)
    • 1. they are not abundant (1 in 50K cells)
    • 2. difficult to grow in vitro
  8. Hematopoiesis occurs at various sites throughout life.
    Where does is occur the first week of development?
    fetal?
    adult?
    where does production decrease after adult stage?
    • yolk sac
    • liver and spleen
    • cranium, pelvis, sternum, ribs, vertebra, long bones
    • long bones
  9. where are HSCs located?
    bone marrow
  10. pluripotent/multipotent
    from one cell, other types of cells can be formed.
  11. unipotent
    can make only one kind of cell
  12. HSCs differentiate into:
    • Lymphoid progenitor cells LPC
    • Myeloid progenitor cells MPCs

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