Gluconeogenesis

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Author:
pszurnicki
ID:
64869
Filename:
Gluconeogenesis
Updated:
2011-02-11 12:44:04
Tags:
Gluconeogenesis
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Description:
Gluconeogenesis
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  1. Gluconeogenesis takes places in what two organs?
    Liver and kidney
  2. Glucose 6 phosphotase is present in what two organs?
    Why?
    • Liver and Kidney?
    • Bc they are responsible for maintaining BSL
  3. Glucose-6-phosphatase is only present where?
    ER of Liver and Kidney
  4. Even or odd chain fatty acids can enter the TCA cycle?
    Odd chain
  5. How can odd chain fatty acids enter the TCA cycle?
    as propionyl coA which is then converted to succinyl-coA
  6. Hereditary Fructose intolerance is caused by what enzyme deficiency?
    Aldolase B
  7. Hereditary fructose intolerance causes what?
    • decrease in P
    • decrease in glycogenlysis
    • decrease in gluconeogenesis
    • hypoglycemia
  8. Essential fructosuria results from what enzyme deficiency?
    how does it present?
    • fructokinase
    • fructose in urine and blood
  9. Enzyme deficiency in Classical Galactosemia?
    symptom?
    • Gal-1 P uridyltransferase
    • galacticol..accumulation in lens
    • hepatosplenomegaly
  10. What is sortbitol?
    • alcohol version of glucose, fructose or galactose
    • Made by alcohol reductase in shwann cells, lens, retina and kidney...those structure dont have sorbitol dyhydrogenase to produce fructose
  11. What stimulates gluconeogenesis?
    • High energy state
    • i.e...ATP, Citrate, acetylcoA
  12. F 1,6 BP and F 2,6 BP stimulate glycolysis or gluconeogenesis
    Glycolysis
  13. What effect does Etoh have on gluconeogenesis?
    It inhibits it

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