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Gluconeogenesis takes places in what two organs?
Liver and kidney
Glucose 6 phosphotase is present in what two organs?
- Liver and Kidney?
- Bc they are responsible for maintaining BSL
Glucose-6-phosphatase is only present where?
ER of Liver and Kidney
Even or odd chain fatty acids can enter the TCA cycle?
How can odd chain fatty acids enter the TCA cycle?
as propionyl coA which is then converted to succinyl-coA
Hereditary Fructose intolerance is caused by what enzyme deficiency?
Hereditary fructose intolerance causes what?
- decrease in P
- decrease in glycogenlysis
- decrease in gluconeogenesis
Essential fructosuria results from what enzyme deficiency?
how does it present?
- fructose in urine and blood
Enzyme deficiency in Classical Galactosemia?
- Gal-1 P uridyltransferase
- galacticol..accumulation in lens
What is sortbitol?
- alcohol version of glucose, fructose or galactose
- Made by alcohol reductase in shwann cells, lens, retina and kidney...those structure dont have sorbitol dyhydrogenase to produce fructose
What stimulates gluconeogenesis?
- High energy state
- i.e...ATP, Citrate, acetylcoA
F 1,6 BP and F 2,6 BP stimulate glycolysis or gluconeogenesis
What effect does Etoh have on gluconeogenesis?
It inhibits it