Pharmacology 8

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  1. What is the main NT issue with Schizophrenia?
    Overactive dopamine pathways.
  2. Clozapine
    • Clozaril
    • Blocks D4 receptors
  3. Haloperidol
    • Haldol
    • Traditional antipsychotic
    • Increased extrapyramidal motor side effects
  4. Fluphenazine
    • Prolixin.
    • Traditional antipsychotic
    • Increased extrapyramidal motor side effects
  5. Chlorpromazine
    • Thorazine
    • Traditional antipsychotic
    • Less potent, causes less motor side effects
    • Has Sedative and anticholinergic effets
  6. Thioridazine
    • Mellaril
    • Traditional antipsychotic
    • Less potent, causes less motor side effects
    • Has Sedative and anticholinergic effets
  7. Clozapine
    • Clozaril
    • Atypical antipsychotic
    • Blocks D2 and has less side effects, usually first choice.
  8. Risperidone
    • Risperdal
    • Atypical antipsychotic
    • Blocks D2 and has less side effects, usually a first choice
  9. If antipsychotic drugs aren't given orally they are usually taken...
    Intramuscular injections "depot administration"
  10. Most feared side effect of antipsychotics
    • Tardive dyskinesia
    • Involuntary and fragmented movements
    • Reserpine is often used to alleviate symptoms
  11. Resting tremor, bradykinesia, rigidity
    Pseudoparkinsonism
  12. Motor restlessness, agitation, insomnia
    • Akathisia
    • Propranolol (Inderal) beta-2 adrenergic receptor blocker is used to help with this side effect
  13. Broad range of involuntary and uncoordinated movements
    • Dyskinesias and dystonias
    • May use antiparkinsons or benzo to treat
  14. NMS
    • Neuroleptic malignant syndrome
    • Catatonia, rigidity, tremor, stupor, fever.
    • Stop the use.

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Author:
Kalanzo
ID:
65170
Filename:
Pharmacology 8
Updated:
2011-02-09 04:34:38
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Pharmacology 8
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