Gluconeogenesis

Card Set Information

Author:
Anonymous
ID:
65301
Filename:
Gluconeogenesis
Updated:
2011-02-09 14:13:01
Tags:
Biochem
Folders:

Description:
Gluconeogenesis
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Anonymous on FreezingBlue Flashcards. What would you like to do?


  1. Definition: Gluconeogenesis
    A pathway for making glucose from noncarbohydrate sources
  2. Why humans need gluconeogenesis
    • to convert lactic acid made in muscle and other cells back into glucose (liver does 90% of this
    • conversion, kidney 10%)
    • to make glucose for brain when carbohydrates are not readily available, eg. when diet is low in carbohydrate (brain uses glucose as main energy
    • source)
    • to make glucose and other sugars for glycoproteins
  3. Where does gluconeogenesis take place
    • 90% in the liver
    • 10% in the kidney
  4. Name the 4 enzymes that are unique in gluconeogenesis and why they're so special
    • These enzymes are unique because they overcome 3 glycolytic reactions and have strong negative delta G values
    • Pyruvate carboxylase/PEP carboxykinase = these two combined convert pyruvate to PEP through and OAA intermediate
    • Fructose-1,6-bisphosphate = reverses PFK
    • Glucose-6-phosphate = reverses hexokinase
  5. Draw biotin
  6. Biotin's role in gluconeogenesis
    Biotin is used as a cofactor to aid in the transfer of CO2 groups to target various molecules.

What would you like to do?

Home > Flashcards > Print Preview