HMP shunt

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Author:
pszurnicki
ID:
65782
Filename:
HMP shunt
Updated:
2011-02-11 22:13:07
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HMP shunt
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HMP shunt
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  1. Chronic granulomatosis result from what?
    NADPH oxidase
  2. What is the rate limiting step of HMP shunt?
    G6PD
  3. Which part of the HMP shunt is irriversible, the oxidative or nonoxidative part?
    Oxidative
  4. What is the purpose of HMP shunt?
    • NADPH
    • Ribose 5 phosphate
  5. What hormone stimulates the HMP shunt?
    Insulin
  6. Transketolase uses what coenzyme?
    Thiamine--Vit B1
  7. Why would you see a deficient Pyruvate dehydrogenase complex in alcoholics?
    Deficiency in Vit B1---thiamine...a cofactor for Pyruvate dehydrogenase complex
  8. Whats the key enzyme is the nonoxidative part of HMP shunt?
    Transketolase
  9. G6PD deficiency results in what?
    Hemolytic anemia
  10. NADPH is used for what 3 purposes?
    • Regenerate glutathione
    • -cyt 450
    • Oxidative Burst
    • Nitric Oxide synthesis
  11. A deficiency of transketolase would cause an accumulation of what product?
    Ribose 5- Phosphate
  12. What does a branching enzyme do?
    Glycosyl alpha 1,4: alpha 1,6 Transferase

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