MM2

Card Set Information

Author:
Bobopudge
ID:
65819
Filename:
MM2
Updated:
2011-04-09 04:25:02
Tags:
MM Genome DNA structure nucleosome
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Description:
Gene structure
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  1. A bit of DNA that encodes one protein
    gene
  2. How many bonds does A-T form
    2 hydrogen bonds
  3. How many bonds does G-C form?
    3 hydrogen bonds
  4. These bonds hold together the sugar-phosphate backbone
    • Covalent bonds
    • 3'-5' phosphodiester
  5. Temperature at which 50% of DNA melts
    Melting temperature
  6. What is the opposite of denaturing?
    annealing
  7. DNA mixed with proteins is called this
    Chromatin
  8. This protein helps organize DNA
    • Histones
    • 5 types
    • + charged
  9. This histon protein is variable
    H1
  10. A repeating structure in DNA "like beads on a string"
    Nucleosome
  11. What makes up a nucleosome?
    • 200 bp
    • 1 H1
    • 2 of the rest
  12. Nucleosomes coil to make this
    • solenoids
    • aka 30nm fibers
  13. This H-word means "very compact DNA, and cannot be transcribed"
    Heterochromatin
  14. This E-word means "diffused DNA, and can be transcribed"
    Euchromatin
  15. What are the 5 types of Histone proteins?
    • H1
    • H2A
    • H2B
    • H3
    • H4
  16. How do you modify Histone proteins to loosen up the DNA and allow transcription?
    You acetylate them
  17. How do you modify Histone proteins to compact the DNA?
    You methylate them
  18. 3-5 Phosphodiester bonds
  19. DNA structure

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