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What is the composition of ground substance?
- Glycosaminoglycans (GAGs)
- Adhesive glycoproteins (chondronectin)
Where does the growth of long bones occur?
What collagen type is found in hyaline cartilage?
Collagen type II
What collagen type is found in elastic cartilage?
Hyaline cartilage (type II) + elastic fibers
What cartilage type is found in fibrocartilage?
Hyaline cartilage (type II) + collagen type I
What cells produce collagen type II fibrils of hyaline cartilage?
Binding of collagen type II to the ground substance occurs through...
- Negative charges of the GAGs - electrostatic interactions
How do nutrients reach cartilage if it's avascular?
The (-) charge of GAGs pulls nutrients in from the blood vessels of the perichondreum
- Somatotropin C (via Growth Hormone)
Breaks down the protein core of proteoglycans and destroying the rigidity of hyaline cartilage
The area surrounding the lacunar spaces of chondrocytes that's high in proteoglycans/GAGs
The area between chondrocytes that's high in collagen type II
The type of growth that occurs in articular cartilage and on the epiphyseal plate of long bones
The type of cartilage growth that occurs by forming isogenous groups
A ruptured IV disc is caused by rupture of which tissue?
Annulus fibrous tissue ruptures allowing the nucleus pulposus to seep through
Fibrocartilage is found in these 3 locations
- IV discs
- Symphysis pubis
- Menisci of the knee joint
Elastic cartilage is found in these 4 locations
- Pinna of the ear
- External and internal auditory tubules
Perichondreum is not found in these two cartilage types
- Articular cartilage
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