Infections in Immunocompromised Hosts

Card Set Information

Author:
giddyupp
ID:
67201
Filename:
Infections in Immunocompromised Hosts
Updated:
2011-02-17 22:58:58
Tags:
Infections Immunocompromised Hosts PHPR523 Test3
Folders:

Description:
Infections in Immunocompromised Hosts
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user giddyupp on FreezingBlue Flashcards. What would you like to do?


  1. What are the risk factors for developing an infection or becoming an immunocompromised host?
    • medical malnutrition
    • solid organ transplant
    • autoimmune disorders
    • bone marrow transplant
    • RT
    • Corticosteroids
    • Cyclosporine
    • Tacrolimus
    • Etanercept
    • Infliximab
    • Alemtuzumab
    • Fludarabine
    • Cladribine
  2. What is nadir?
    The lowest WBC count after chemotherapy
  3. What is the equation for ANC?
    • WBC x (segs + bands)/100 if percentages
    • [WBC x (segs + bands)]/100 if in totals
    • [WBC x (PMN + bands)]/100
  4. What organisms are most commonly associated with infection in neutropenic pts?
    • S. aureus (and MRSA)
    • S. epidermidis (and MRSE)
    • Streptococcus spp
    • Enterococcus spp
    • Corynebacterium spp
    • Bacillus spp
    • P. aeruginosa
    • B. cepacia
    • E. coli
    • Klebsiella spp
    • Acinetobacter baumannii
    • Serratia spp
    • Enterobacter spp
    • Citrobacter spp
    • Salmonella spp
    • Proteus spp
    • Stenotrophomonas maltophila
    • Bacteroides spp
    • C. difficile
    • Fusobacterium spp
    • Propionibacterium spp
    • Veillonella spp
    • Peptococcus spp
    • Peptostreptococcus spp
    • Candida spp
    • Aspergillus spp
    • Zygomycetes rhizopus
    • Zygomycetes mucor
    • Coccidioides spp
    • Blastomyces spp
    • Histoplasma spp
    • Influenza
    • Parainfluenza
    • HSV
    • Vericella zoster
    • CMV
    • Hep B
    • RSV
    • P. jirovecii
    • T. gondii
  5. What is the prophylactic tx for febrile neutropenic (<500) pts at low risk?
    • Cipro + Amoxicillin clavulanate (Clindamycin for Pen allergy)
    • Cefepime
    • Ceftazidime
    • Carbapenem
    • AG + Antipseudomonal pen
    • AG + Cefepime
    • AG + Ceftazidime
    • AG + Carbapenem
    • Reassess in 3-5d
  6. What is the prophylactic tx for febrile neutropenic (<500) pts at high risk?
    • Cefepime
    • Ceftazidime
    • Carbapenem
    • AG + Antipseudomonal pen
    • AG + Cefepime
    • AG + Ceftazidime
    • AG + Carbapenem
    • Vanco + Cefepime
    • Vanco + Ceftazidime
    • Vanco + Carbapenem
    • Reassess after 3-5d
  7. What's the next step in tx if pt is afebrile after 3-5d with no etiology identified?
    • Low risk:
    • Cipro + Amox clav (Cefixime for kids)
    • High risk: continue same ABX
    • Then discharge
  8. What's the next step in tx if pt is afebrile after 3-5d with etiology identified?
    Adjust to most appropriate tx
  9. What is the next step in tx if pt is still febrile after 3-5d and no etiology identified?
    • Reassess every day 3-5
    • Continue initial ABX:
    • if no change (also consider stopping Vanco)
    • Change ABX:
    • if progressive disease
    • if criteria for Vanco are met
    • Antifungal drug, with or without ABX change:
    • if febrile through days 5-7 and resolution of neutropenia is not imminent
  10. How long should ABX tx continue if afebrile by days 3-5?
    • 48h after afebrile + ANC at least 500
    • 5-7d after afebrile if ANC < 500 and initial risk was low
    • continue ABX if ANC < 500 and initial risk was high
  11. How long should ABX tx continue if fever persistant?
    • 4-5d after ANC > 500 and reassess
    • Reassess after 2wks if ANC < 500, no disease present, and condition is stable

What would you like to do?

Home > Flashcards > Print Preview