Pharm

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Author:
felizdiaz
ID:
67309
Filename:
Pharm
Updated:
2011-02-18 13:52:23
Tags:
barbit
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Description:
barbit
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  1. ULTRA SHORT BARBITURATES
    THIOPENTAL, THIAMYLAL, METHOHEXITAL
  2. WHY AND WHAT ARE BARBIT INCOMPATIBLE?
    DT HIGH ACIDICITY THEY DON'T WORK WITH OPIOIDS, CATECHOLAMINES, AND NMB
  3. OXYBARBIT VS THIOBARBIT
    THIO ARE MORE LIPID, HIGER POTENCY, FASTER ONSET, SHORTER DURATION.
  4. WHERE DOES BARBIT WORK AT
    AT THE GABA RECEPTOR THAT ACITIVATES THE CHLORIDE CHANNES TO OPEN MAKE THE MEMBRANE HYPERPOLARIZED
  5. LEAN BODY WEIGHT
    • MALE- 60 + (2.3X INCH OVER60)
    • FEMALE 45.5 + "" "" "" ''' ''
  6. METABOLISM OF THIOPENTAL VS METHOHEXITAL
    THIO IS ENZYME DEPENDANT AND METH IS BLOOD FLOW DEPENDANT.
  7. ONLY BARBIT THAT IS RENAL EXCRETION
    PHENOBARITAL
  8. CLINICAL USES OF BARBIT
    • DECREASE ICP
    • INDUCTIONS
    • TX HYPERBILIRU AND KERNINCTERUS WITH PHENO
  9. DISADVAN OF METHOHEXITAL
    MYOLONUS, HICCOUGH, 33% SEIZURES,
  10. HOW DOES BARBIT TX INCREASE ICP
    • WITH DUIRESIS AND HYPERVENT
    • DECRE BRAIN BLOOD FLOW, AND INDUCE CEREBO VASOCONCTRICTION, O2 NEED,
  11. SE OF BARBIT
    • LOW BP,
    • HEART DEPRESSION
    • HISTAMIN RELEASE
    • NOT FOR LOW VOL PT
    • RESP DEPRESSION
    • NO THIOPENTAL FOR INTERMITTENT PUR
    • ACUTE TOLERANCE
  12. ANAPHYLACTIOD REACTION
    NOT A TRUE REACTION (IMMUNE) BUT STILL HAVE HISTAMINE RELEASE, VASO DILUATION, WHEALS, WELTS.
  13. PROPOFOL NERUO AND EYE
    • ANTICONVULSANT
    • DECREASE CERE METABOLIC, ICP, BLOOD FLOW

    DECREASE IOP,
  14. PROPOFOL CARDIO AND LUNGS
    • DECREASE IN BP (AVOID WITH LOW VOL)
    • MAY CAUSE PROFOUND LOW HR
  15. VENT DEPRESSION
  16. ETOMIDATE CNS AND LUNG
    • DECREASE ICP
    • CAUTION WITH FOCAL SEIZURES

    VENT DEPRESSION
  17. ETOMIDATE CARDIO, RENAL
    • MINIMAL CHANGES TO HR, SV, CO
    • CAUTION WITH LOW VOL

    MINIMAL EFFECTS ON RENAL BF
  18. ETOMIDATE SE
    • MYOCLONUS, HICCOUGHS
    • ADRENOCORTICAL SUPPRESSION
  19. HOW IS KETAMINE UNLIKE OTHER MEDICATION
    • WORKS ON NMDA NOT GABA
    • INTENSE ANALGESIA
    • CARDIO STIMULANT
  20. EMERGENCE DELIRUM WITH KETAMINE
    CAN PREVENT WITH VERSED 5 MIN A

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