Block 3 Lipids

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pszurnicki
ID:
67363
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Block 3 Lipids
Updated:
2011-02-21 17:12:40
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Block Lipids
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Block 3 Lipids
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  1. FA are amphipathic, what does it mean?
    They have hydrophilic and hydrophobic parts
  2. How many carbons is palmitoyl acid?
    16
  3. How many carbons is stearic acid?
    18
  4. How many carbons is arachidonic acid?
    20
  5. What are the 3 ketone bodies?
    • Acetone
    • Acetoacetate
    • 3- hydroxybutarate
  6. Linolenic acid is how many carbons?
    18
  7. What are the essential FA?
    • Linoleic
    • Linolenic
  8. What is the rate determining enzyme for FA degradation?
    Carnitine acyltransferase I
  9. What is the rate determining enzyme for FA synthesis?
    • Acetyl CoA carboxylase
    • Needs Biotin
  10. FA synthesis occurs where?
    Cytosol
  11. FA degradation occurs where?
    Mitochondria
  12. Synthetic intermediates are carried by what?
    acyl carrier protein(ACP)
  13. Degradation products are carried by what?
    Coenzyme A
  14. Allosteric Inhibition of what enzyme allows citrate to diffuse out of the mitochondria?
    Isocitrate dehydrogenase
  15. What enzyme converts citrate to acetyl coa on the cytosolic side?
    ATP-dependent Citrate Lyase
  16. What activates acetyl coA carboxylase?
    citrate
  17. What deactivates acetyl CoA carboxylase?
    LCFA-CoA
  18. What effect does glucagon have on acetyl coA carboxylase?
    Deactivates it by phosphorylating it
  19. What effect does high carbohydrate diet have on ACC?
    High carbohydrate diet upregulates the expression of ACC
  20. What effect does insulin have on ACC?
    It dephosphorylates it by activating phosphotases
  21. In the cytosol, ACC converts acetyl coA into?
    malonyl coA
  22. What gene is sometimes upregulated in breast cancers that has to do with fatty acid synthesis?
    FAS--fatty acid synthase
  23. Paroxysmal Nocturnal Hemoglobinuria
    PICA gene mutation
  24. What FA is needed for prostoglandin synthesis?
    Arachidonic acid
  25. Sphingomyelinase deficiency results in what?
    Nieman-Pick Disease
  26. Glycosphingolipid unlike sphingomyelin does not contain what?
    Phosphate
  27. Types of Glycosphingolipids?
    • cerebrosides
    • globosides
    • gangliosides
  28. Cerebrosides are what type of monosaccharides?
    Ceramide
  29. Example of an acidic glycerophospholipid?
    Ganglioside
  30. Surfactant A is a what type of complex lipid?
    Lecitin

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