MM3

Card Set Information

Author:
Bobopudge
ID:
67422
Filename:
MM3
Updated:
2011-04-09 04:58:30
Tags:
MM Meiosis
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Description:
Cell Cycle, Meiosis
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  1. This phase is everything except mitosis
    interphase
  2. Chromosomes condense
    Prophase
  3. Nuclear envelope goes away in this stage
    pro-metaphase
  4. Chromosomes line up on metapase plate
    metaphase
  5. Centromeres split and chromosomes pulled to opposite sides
    anaphase
  6. Chromosomes de-condense, nuclear membrane returns, and cells divide
    telophase
  7. This is where spindles attach chromosomes
    centromeres
  8. 5 Bits of Prophase
    Lepotene: unpaired but replicated chromosomes can be seen

    Zygotene: maternal and paternal homologs pair up and synapse so genes are along eachother = bivalents

    Pachytene: chromosomes thicken, crossing over occurs

    Diplotene: homologs try to separate but are held together by chiasmata here

    Diakenisis: homologous pairs contract
  9. This holds homologs together in metaphase 1
    chiasmata
  10. Crossing over happens at these sites
    chiasmata
  11. Exchange of genetic information between non-sister chromatids
    Crossing over
  12. Sister chromatids are pulled apart
    anaphase 2
  13. Homologous chromosomes line up
    metaphase 1
  14. Chromosomes with the same length, centromere position, and genes
    • Homologous chromosomes
    • One from dad, one from mom
  15. What are two sources of genetic variation?
    1. independent assortment

    2. Cossing over
  16. This complex polices the G1 --> S phase
    • Cdk2-CyclinA complex
    • If there is damaged DNA, S-phase will not begin
  17. This enzyme is important in apoptosis
    Caspase
    • Cyclins are scaffolding proteins
    • they bring target proteins close to CDK for interaction
  18. In late G1 phase, Cyclin A - CDK2 complex activates a transcription factor called E2F so that mitosis can occur

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